ReviewNeuroscience and biobehavioral reviews2015
How do mammillary body inputs contribute to anterior thalamic function?
Review in Neuroscience and biobehavioral reviews, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Two Molecularly Defined Neuronal Types in the Mammillary Body Govern Different Temporal Periods during Working Memory Maintenance.Research (Washington, D.C.) · 2026Article
- Deep brain stimulation of the anterior nucleus of the thalamus in animal models of mesial temporal lobe epilepsy: A literature review.Epilepsy research · 2025Review
- A dorsal subiculum-medial mammillary body pathway for spatial memory.Molecular psychiatry · 2025Article
- Impairments of spatial memory retrieval via medial mammillary body dysfunction in Alzheimer's disease model.Translational psychiatry · 2025Article
- Two distinct cell types of the medial mammillary body forming segregated subcircuits.Molecular psychiatry · 2025Article
- Early onset of hyperexcitability of medial mammillary body neurons in 5XFADJournal of neurophysiology · 2025Article
- Parvalbumin Neurons in the Basal Forebrain Projecting to the Mammillary Nucleus Ameliorate Age-Related Cognitive Decline.International journal of molecular sciences · 2025Article
- Projectome-based characterization of hypothalamic peptidergic neurons in male mice.Nature neuroscience · 2025Article
- Article
- Cell-Type Specific Circuits in the Mammillary Body for Place and Object Recognition Memory.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Unique amnestic syndrome after isolated left anterolateral thalamic stroke: a case report.BMC neurology · 2025Article
- Article
- A reappraisal of the role of the mammillothalamic tract in memory deficits following stroke in the thalamus.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Establishing connectivity through microdissections of midbrain stimulation-related neural circuits.Brain : a journal of neurology · 2024Article
- Electrophysiological Properties of the Medial Mammillary Bodies across the Sleep-Wake Cycle.eNeuro · 2024Article
- Mammillary body abnormalities and cognitive outcomes in children cooled for neonatal encephalopathy.Developmental medicine and child neurology · 2023Article
- The Cortico-Limbo-Thalamo-Cortical Circuits: An Update to the Original Papez Circuit of the Human Limbic System.Brain topography · 2023Review
- Changes in the superior longitudinal fasciculus and anterior thalamic radiation in the left brain are associated with developmental dyscalculia.Frontiers in human neuroscience · 2023Article
- Collateral rostral thalamic projections to prelimbic, infralimbic, anterior cingulate and retrosplenial cortices in the rat brain.The European journal of neuroscience · 2022Article
- Time to retire the serial Papez circuit: Implications for space, memory, and attention.Neuroscience and biobehavioral reviews · 2022Review
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Authors and funding
4 authors.
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Abstract
It has long been assumed that the main function of the mammillary bodies is to provide a relay for indirect hippocampal inputs to the anterior thalamic nuclei. Such models afford the mammillary bodies no independent role in memory and overlook the importance of their other, non-hippocampal, inputs. This review focuses on recent advances that herald a new understanding of the importance of the mammillary bodies, and their inputs from the limbic midbrain, for anterior thalamic function. It has become apparent that the mammillary bodies' contribution to memory is not dependent on afferents from the subicular complex. Rather, the ventral tegmental nucleus of Gudden is a vital source of inputs that support memory processes within the medial mammillary bodies. In parallel, the lateral mammillary bodies, via their connections with the dorsal tegmental nucleus of Gudden, are critical for generating head-direction signals. These two parallel, but distinct, information streams converge on the anterior thalamic nuclei and support different aspects of spatial memory.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.