ArticleSleep & breathing = Schlaf & Atmung2015
Serum levels of trace minerals and heavy metals in severe obstructive sleep apnea patients: correlates and clinical implications.
Article in Sleep & breathing = Schlaf & Atmung, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 30 citations in OpenAlex.
- Exposure to environmental toxicants and obstructive sleep apnea: a cross-sectional study.Future science OA · 2026Article
- Article
- Association Between Serum Trace Elements and Obstructive Sleep Apnea in Iranian Adults: Multiple-exposure Models.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2026Article
- Insights Into the Separate and Joint Effects of Cadmium and Cesium on the Risk of Circadian Syndrome and the Underlying Mechanism: An Integrated Epidemiological and Network Toxicological Study.Biological trace element research · 2026Article
- Magnesium and Zinc Are Associated with Sleep Quality in Saudi Adults: Evidence from a Cross-Sectional Study.Nutrients · 2025Article
- Associations of a metal mixture and vitamin D with sleep duration among adolescents and young adults from the 2011-2018 NHANES cycles.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025Article
- Effects of Cadmium and Lead Co-exposure on Sleep Status in Rural Areas Northwestern China.Biological trace element research · 2025Article
- Sleep duration mediates the association between heavy metals and the prevalence of depression: an integrated approach from the NHANES (2005-2020).Frontiers in psychiatry · 2024Article
- Analysis of the relationship between sleep-related disorders and cadmium in the US population.Frontiers in public health · 2024Article
- Manganese and Sleep Outcomes in United States Adults: Results from the 2017-2020 National Health and Nutrition Examination Survey (NHANES).The Journal of nutrition · 2024Article
- Disparities in Sleep-Disordered Breathing: Upstream Risk Factors, Mechanisms, and Implications.Clinics in chest medicine · 2023Review
- Mitigation role of physical exercise participation in the relationship between blood cadmium and sleep disturbance: a cross-sectional study.BMC public health · 2023Article
- The Effect of Cadmium on Sleep Parameters Assessed in Polysomnographic Studies: A Case-Control Study.Journal of clinical medicine · 2023Article
- Association between serum trace elements and sleep disturbance in patients with decompensated cirrhosis.Therapeutic advances in chronic disease · 2023Article
- The association of cobalturia with cobaltism symptoms a prospective blinded study of 229 post-arthroplasty patients.PloS one · 2023Article
- Urinary polycyclic aromatic hydrocarbon metabolites were associated with short sleep duration and self-reported trouble sleeping in US adults: data from NHANES 2005-2016 study population.Frontiers in public health · 2023Article
- Serum Magnesium Levels in Patients with Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis.Biomedicines · 2022Review
- Environmental exposures and sleep outcomes: A review of evidence, potential mechanisms, and implications.Environmental research · 2021Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of the present study was to evaluate the serum levels of trace minerals and heavy metals in obstructive sleep apnea (OSA) patients and to investigate whether there is a correlation between levels of trace minerals and demographic and biochemical variables.
methodsThis clinical, case-control study was performed on 61 OSA patients and 36 healthy controls. Demographic, radiological, biochemical variables, as well as serum levels of trace minerals (magnesium, copper, iron, zinc, manganese, cobalt) and heavy metals (lead, cadmium) were compared in OSA and control groups. In addition, correlation of serum levels of these substances to demographic, biochemical, and radiological parameters was tested.
resultsNot only serum levels of cholesterol, triglycerides, cadmium, cobalt, copper, iron, magnesium, manganese, lead, and zinc were found to be higher, but also carotid intima-media thickness (CIMT) was increased in OSA patients. Increase in CIMT was found to be correlated with levels of cobalt, copper, iron, magnesium, manganese, and zinc.
conclusionOur results have shown that serum levels of trace minerals and heavy metals were higher in OSA. This difference may ensource from deterioration of the balance of these substances due to oxidative stress and inflammation. Significance of these findings with respect to the etiopathogenesis, diagnosis, and treatment of OSA warrants further trials.
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