ArticlePsychiatry research2014
Distress intolerance and clinical functioning in persons with schizophrenia.
Article in Psychiatry research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Managing emotions in psychosis: Evaluation of a brief DBT-informed skills group for individuals with psychosis in routine community services.The British journal of clinical psychology · 2022Trial
- Levels of distress tolerance in schizophrenia appear equivalent to those found in borderline personality disorder.Journal of clinical psychology · 2020Trial
- Psychological stress induced mitochondrial response in humans and its medial prefrontal biomarker correlates.Translational psychiatry · 2026Article
- Blood and neuronal extracellular vesicle mitochondrial disruptions in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Stress sensitivity, negative affect, and functioning in an early psychosis clinic.Schizophrenia research · 2025Article
- Impact of psychosocial stress on facial emotion recognition in schizophrenia and controls: an experimental study in a forensic sample.Frontiers in psychiatry · 2024Article
- A Mobile Health App (ChillTime) Promoting Emotion Regulation in Dual Disorders: Acceptability and Feasibility Pilot Study.JMIR formative research · 2023Article
- Abnormal cortisol profile during psychosocial stress among patients with schizophrenia in a Chinese population.Scientific reports · 2022Article
- Social Connectedness in Schizotypy: The Role of Cognitive and Affective Empathy.Behavioral sciences (Basel, Switzerland) · 2022Article
- Domains of Vulnerability, Resilience, Health Habits, and Mental and Physical Health for Health Disparities Research.Behavioral sciences (Basel, Switzerland) · 2022Article
- An examination of neurocognition and theory of mind as predictors of engagement with a tailored digital therapeutic in persons with serious mental illness.Schizophrenia research. Cognition · 2022Article
- Aberrant anterior cingulate processing of anticipated threat as a mechanism for psychosis.Psychiatry research. Neuroimaging · 2021Article
- Cingulum and abnormal psychological stress response in schizophrenia.Brain imaging and behavior · 2020Article
- The Fragile Brain: Stress Vulnerability, Negative Affect and GABAergic Neurocircuits in Psychosis.Schizophrenia bulletin · 2019Review
- Salivary kynurenic acid response to psychological stress: inverse relationship to cortical glutamate in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018Article
- Metacognitive self-reflectivity moderates the relationship between distress tolerance and empathy in schizophrenia.Psychiatry research · 2018Article
- Obsessive-compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings.European archives of psychiatry and clinical neuroscience · 2018Article
- Disrupted glucocorticoid--Immune interactions during stress response in schizophrenia.Psychoneuroendocrinology · 2016Article
- Cumulative stress pathophysiology in schizophrenia as indexed by allostatic load.Psychoneuroendocrinology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Impaired tolerance to distress may help explain part of the cognitive and functional impairments in schizophrenia (SZ). This project investigated distress intolerance in SZ patients as compared to controls, and whether distress intolerance represented an independent domain in relationship to symptoms, cognition, and functional capacity. Healthy controls (n=43) and SZ (n=65) completed a psychological distress challenge experiment and their levels of intolerance to distress were estimated. SZ showed increased distress intolerance such that they were significantly more likely to terminate the distress challenge session early compared to controls. Greater distress intolerance was associated with reduced functional capacity and worse cognitive performance in SZ. Mediation analyses suggested that distress intolerance had an independent effect on functional capacity, while some of this effect was mediated by cognitive performance. Our results suggest that distress intolerance is a promising domain for treatment research, and functional capacity may be improved by targeting treatments towards SZ patient׳s ability to tolerate distress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.