ReviewMycopathologia2014
Neutrophil responses to aspergillosis: new roles for old players.
Review in Mycopathologia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Pathogenicity and virulence ofVirulence · 2023Review
- Deciphering the Role of PIG1 and DHN-Melanin inJournal of fungi (Basel, Switzerland) · 2023Article
- Article
- Immunosuppression Affects Neutrophil Functions: Does Calcineurin-NFAT Signaling Matter?Frontiers in immunology · 2021Review
- Review
- How Long Do We Need to Treat an Invasive Mold Disease in Hematology Patients? Factors Influencing Duration of Therapy and Future Questions.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
- 12/15-Lipoxygenase Deficiency Impairs Neutrophil Granulopoiesis and Lung Proinflammatory Responses toJournal of immunology (Baltimore, Md. : 1950) · 2020Article
- Bronchial Epithelial Cells on the Front Line to Fight Lung Infection-CausingFrontiers in immunology · 2020Review
- Animal Models of Aspergillosis.Comparative medicine · 2018Review
- Preparations for Invasion: Modulation of Host Lung Immunity During PulmonaryFrontiers in immunology · 2018Review
- Natural Killer Cells in Antifungal Immunity.Frontiers in immunology · 2017Review
- The Absence of NOD1 Enhances Killing ofFrontiers in immunology · 2017Article
- FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection.PLoS pathogens · 2016Article
- The First Case of Invasive Mixed-Mold Infections Due to Emericella nidulans var. echinulata and Rasamsonia piperina in a Patient with Chronic Granulomatous Disease.Mycopathologia · 2016Article
- Human Neutrophils Are Primed by Chemoattractant Gradients for Blocking the Growth of Aspergillus fumigatus.The Journal of infectious diseases · 2016Article
- Corpora Amylacea of Brain Tissue from Neurodegenerative Diseases Are Stained with Specific Antifungal Antibodies.Frontiers in neuroscience · 2016Article
- Defining the transcriptomic landscape of Candida glabrata by RNA-Seq.Nucleic acids research · 2015Article
- Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis.Frontiers in microbiology · 2015Review
- Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions.Frontiers in microbiology · 2015Article
- Advances against aspergillosis: biology, host response, diagnosis and treatment.Mycopathologia · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neutrophils are professional phagocytic cells that play a crucial role in innate immunity. Through an assortment of antifungal effector mechanisms, neutrophils are essential in controlling the early stages of fungal infection. These mechanisms range from the production of reactive oxygen intermediates and release of antimicrobial enzymes to the formation of complex extracellular traps that aid in the elimination of the fungus. Their importance in antifungal immunity is supported by the extreme susceptibility to infection of patients with primary (e.g., chronic granulomatous disease) or acquired (e.g., undergoing immunosuppressive therapy) neutrophil deficiency. More recently, common genetic variants affecting neutrophil antifungal capacity have also been disclosed as major risk factors for aspergillosis in conditions of generalized immune deficiency. The present review revisits the role of neutrophils in the host response against Aspergillus and highlights the consequences of their deficiency in susceptibility to aspergillosis.
Indexed as
Identifiers
25106756What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.