Trial reportSurgical endoscopy2015
Laparoscopic versus open resection for colon cancer: 10-year outcomes of a prospective clinical trial.
Trial report in Surgical endoscopy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Safety and oncological outcomes of natural orifice specimen extraction surgery compared with conventional laparoscopic surgery for right hemicolectomy: a systematic review and meta-analysis.Updates in surgery · 2022Pooled it
- Colorectal resection via natural orifice specimen extraction versus conventional laparoscopic extraction: a meta-analysis with meta-regression.Techniques in coloproctology · 2021Pooled it
- Meta-analysis of laparoscopic anterior resection with natural orifice specimen extraction (NOSE-LAR) versus abdominal incision specimen extraction (AISE-LAR) for sigmoid or rectal tumors.World journal of surgical oncology · 2020Pooled it
- Preoperative localization of colorectal cancer: a systematic review and meta-analysis.Surgical endoscopy · 2017Pooled it
- Intracorporeal anastomosis versus extracorporeal anastomosis for laparoscopic right hemicolectomy: short-term and long-term outcomes.Surgical endoscopy · 2026Article
- Is minimally invasive surgery safe and effective for pT4 colon cancer? Results from a national retrospective cohort study.Surgical endoscopy · 2026Article
- Laparoscopic natural orifice specimen extraction, a minimally invasive surgical technique for mid-rectal cancers: Retrospective single-center analysis and single-surgeon experience of selected patients.The Journal of international medical research · 2022Article
- Surgical Management of Sigmoid Volvulus: A Multicenter Observational Study.Annals of coloproctology · 2020Article
- The Comparison of Laparoscopic Colorectal Resection with Natural Orifice Specimen Extraction versus Mini-Laparotomy Specimen Extraction for Colorectal Tumours: A Systematic Review and Meta-Analysis of Short-Term Outcomes.Journal of oncology · 2020Article
- Short-term outcomes after elective colon cancer surgery: an observational study from the Norwegian registry for gastrointestinal and HPB surgery, NoRGast.Surgical endoscopy · 2019Observational
- Intra-corporeal delta-shaped anastomosis in laparoscopic right hemicolectomy for right colon cancer: a safe and effective technique.Gastroenterology report · 2019Article
- Comparing short-time outcomes of three-dimensional and two-dimensional totally laparoscopic surgery for colon cancer using overlapped delta-shaped anastomosis.OncoTargets and therapy · 2019Article
- Laparoscopic conversion in colorectal cancer surgery; is there any improvement over time at a population level?Surgical endoscopy · 2018Article
- Laparoscopic right-sided colon resection for colon cancer-has the control group so far been chosen correctly?World journal of surgical oncology · 2018Article
- Development and validation of a preoperative prediction model for colorectal cancer T-staging based on MDCT images and clinical information.Oncotarget · 2017Article
- Real-world cost-effectiveness of laparoscopy versus open colectomy for colon cancer: a nationwide population-based study.Surgical endoscopy · 2017Article
- Nationwide implementation of laparoscopic surgery for colon cancer: short-term outcomes and long-term survival in a population-based cohort.Surgical endoscopy · 2016Article
- Reduced port laparoscopic surgery for colon cancer is safe and feasible in terms of short-term outcomes: comparative study with conventional multiport laparoscopic surgery.Annals of surgical treatment and research · 2016Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic resection (LR) and open resection (OR) for colon cancer have similar oncologic outcomes at 5-year follow-up. However, results from studies with longer follow-up are limited. This study aimed to compare 10-year oncologic outcomes of LR and OR for non-metastatic colon cancer.
methodsA prospective non-randomized trial comparing patients undergoing LR or OR for non-metastatic colon cancer at a single institution was conducted. Statistical analyses were performed on an ''intention-to-treat'' basis and by actual treatment. Kaplan-Meier curves were compared to analyze overall survival (OS) and disease-free survival (DFS). A multivariate analysis was performed to identify predictors of poor survival.
resultsThe study included 304 colon cancer patients: 154 patients underwent LR and 150 underwent OR. Fifteen (9.7 %) had LR converted to OR. During a median follow-up period of 138 (range, 120-220) months, no significant differences were observed between LR and OR patients in 10-year OS and DFS rates: 87.2 % versus 78.7 % (P = 0.182) and 80.9 % versus 76.8 % (P = 0.444), respectively. Conversion to open surgery was associated with a non-significant reduction in OS and DFS. Stage-by-stage comparison showed no significant differences between the two groups. Both OS and DFS were similar between right colon and left-sided colon cancer patients. On multivariate analysis, pT4 cancer and a lymph node ratio of 0.20 or more were the only independent predictors of both OS and DFS.
conclusionsThe 10-year follow-up results confirm the oncological effectiveness of the laparoscopic approach to non-metastatic colon cancer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.