Evidence map›Paper›PMID 25106486›Full record

ArticleEuropean radiology2014

Ultrafast cone-beam computed tomography imaging and postprocessing data during image-guided therapeutic practice.

Jijo Paul, Emmanuel C Mbalisike, Thomas J Vogl

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. New concepts in embolotherapy of HCC.Medical oncology (Northwood, London, England) · 2017
    Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jijo PaulDiagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt/Main, Germany, jijopaul1980@gmail.com.
Emmanuel C Mbalisike
Thomas J Vogl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOur objective was to evaluate ultrafast cone-beam computed tomography (u-CBCT) image data using cross-sectional images, perfusion blood volume (PBV), and image fusion during tumour detection at the course of transarterial chemoembolization.

methodsOne hundred and fifty patients (63 ± 20 years; 33-82) were examined from February to October 2013 with u-CBCT. Tumour delineation and conspicuity were determined using u-CBCT cross-sectional PBV and u-CBCT-magnetic resonance imaging (MRI) fused data sets for hyperenhanced (HYET), heterogeneously enhanced (HEET), and unenhanced (UET) tumour categories. Catheter localisation and tumour feeding vessels were assessed using all data sets. Quantitative and qualitative analyses were performed using appropriate statistical tests.

resultQualitative and quantitative tumour delineation showed significant difference (all P < 0.05) among tumour categories. Mean tumour-liver-contrast was higher in HYET than in HEET, and UET; moreover, differences between tumour categories were statistically significant (all P < 0.0001). Fused data showed higher value with statistical significance (P < 0.05) compared with other data sets during catheter localisation and feeding-vessel identification.

conclusionTumour delineation was clearly possible using u-CBCT cross sections with contrast material. PBV uses color-coded images to increase detection and produces good tumour differentiation. Image fusion helps accurately identify tumour and feeding vessels and locate contrast material injection sites and catheter tips without additional data acquisition. KEY POINTS: • Ultrafast CBCT cross-sectional data provide good tumour delineation with contrast material • Postprocessed PBV using u-CBCT increased detectability and tumour differentiation • u-CBCT cross-sectional PBV and u-CBCT-MRI data helps image guidance during chemoembolization • u-CBCT-MRI can identify tumours and feeding vessels and locate catheter tip accurately.

Indexed as

AdultAgedAged, 80 and overAntineoplastic AgentsBlood Volume DeterminationChemoembolization, TherapeuticCone-Beam Computed TomographyContrast MediaFemaleHumansLiver NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedRadiation DosageRetrospective StudiesAntineoplastic AgentsContrast Media

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.