ArticleVirology journal2014
Identification of a novel nidovirus in an outbreak of fatal respiratory disease in ball pythons (Python regius).
Article in Virology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Evolutionarily divergent nidovirus with an exceptionally large genome identified in Pacific oysters undergoing mass mortality.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Identifying Infectious Agents in Snakes (Boidae and Pythonidae) with and Without Respiratory Disease.Animals : an open access journal from MDPI · 2025Article
- First case of serpentovirus infection in a ball python (Veterinary research forum : an international quarterly journal · 2025Article
- Identification and Characterization of Novel Serpentoviruses in Viperid and Elapid Snakes.Viruses · 2024Article
- Serpentoviruses Exhibit Diverse Organization and ORF Composition with Evidence of Recombination.Viruses · 2024Article
- Review
- Divergent Serpentoviruses in Free-Ranging Invasive Pythons and Native Colubrids in Southern Florida, United States.Viruses · 2022Article
- Nidoviruses in Reptiles: A Review.Frontiers in veterinary science · 2021Review
- Serpentovirus (Nidovirus) and Orthoreovirus Coinfection in Captive Veiled Chameleons (Viruses · 2020Article
- Serpentoviruses: More than Respiratory Pathogens.Journal of virology · 2020Article
- A case report of reptile-associated nidovirus (serpentovirus) in a ball python (Python regius) in Taiwan.The Journal of veterinary medical science · 2020Article
- Blind Trading: A Literature Review of Research Addressing the Welfare of Ball Pythons in the Exotic Pet Trade.Animals : an open access journal from MDPI · 2020Review
- Investigations into the presence of nidoviruses in pythons.Virology journal · 2020Article
- Polyglutamine Repeats in Viruses.Molecular neurobiology · 2019Review
- Longitudinal and Cross-Sectional Sampling of Serpentovirus (Nidovirus) Infection in Captive Snakes Reveals High Prevalence, Persistent Infection, and Increased Mortality in Pythons and Divergent Serpentovirus Infection in Boas and Colubrids.Frontiers in veterinary science · 2019Article
- A decade of RNA virus metagenomics is (not) enough.Virus research · 2018Review
- Article
- Article
- Nidovirus-Associated Proliferative Pneumonia in the Green Tree Python (Morelia viridis).Journal of virology · 2017Article
- Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRespiratory infections are important causes of morbidity and mortality in reptiles; however, the causative agents are only infrequently identified.
findingsPneumonia, tracheitis and esophagitis were reported in a collection of ball pythons (Python regius). Eight of 12 snakes had evidence of bacterial pneumonia. High-throughput sequencing of total extracted nucleic acids from lung, esophagus and spleen revealed a novel nidovirus. PCR indicated the presence of viral RNA in lung, trachea, esophagus, liver, and spleen. In situ hybridization confirmed the presence of intracellular, intracytoplasmic viral nucleic acids in the lungs of infected snakes. Phylogenetic analysis based on a 1,136 amino acid segment of the polyprotein suggests that this virus may represent a new species in the subfamily Torovirinae.
conclusionsThis report of a novel nidovirus in ball pythons may provide insight into the pathogenesis of respiratory disease in this species and enhances our knowledge of the diversity of nidoviruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.