ArticleInflammatory bowel diseases2014
The impact of hormonal contraception on disease-related cyclical symptoms in women with inflammatory bowel diseases.
Article in Inflammatory bowel diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Role of environmental factors in the pathogenesis of Crohn's disease: a critical review.International journal of colorectal disease · 2019Pooled it
- Systematic review: the consequences of psychosocial effects of inflammatory bowel disease on patients' reproductive health.Alimentary pharmacology & therapeutics · 2018Pooled it
- Understanding Inflammatory Bowel Disease in Women From Puberty to Menopause.Gastroenterology & hepatology · 2025Article
- Reproductive and sexual health concerns in gastrointestinal illness: a narrative review.Translational gastroenterology and hepatology · 2025Review
- High Use of Estrogen-based Contraceptives in Young Women With Inflammatory Bowel Disease in the United States.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024Article
- Impact of inflammatory bowel disease on women's reproductive life: a questionnaire-based study.Therapeutic advances in gastroenterology · 2024Article
- [How Should We Do Different Approach to Treat Inflammatory Bowel Disease by Gender Difference?]The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2021Review
- Correlation of menstrual distress to severity of gastrointestinal symptoms in inflammatory bowel disease patients.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020Article
- Hormone Therapy for Cancer Is a Risk Factor for Relapse of Inflammatory Bowel Diseases.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2020Article
- The Risk of Cerebrovascular Accidents in Inflammatory Bowel Disease in the United States: A Population-Based National Study.Clinical and experimental gastroenterology · 2020Article
- Change in bowel habits during menstruation: are IBD patients different?Therapeutic advances in gastroenterology · 2020Article
- Contraceptive Use in Women With Inflammatory Bowel Disease.Gastroenterology & hepatology · 2018Article
- Updates on Women's Health Issues in Patients with Inflammatory Bowel Disease.Current treatment options in gastroenterology · 2018Review
- The Influence of Hormonal Fluctuation on Inflammatory Bowel Disease Symptom Severity-A Cross-Sectional Cohort Study.Inflammatory bowel diseases · 2018Article
- Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease.Digestive diseases and sciences · 2017Article
- Hormonal Contraception Use is Common Among Patients with Inflammatory Bowel Diseases and an Elevated Risk of Deep Vein Thrombosis.Inflammatory bowel diseases · 2016Article
- Sexual satisfaction and inflammatory bowel diseases: an interdisciplinary clinical challenge.American journal of obstetrics and gynecology · 2016Article
- Fertility and Contraception in Women With Inflammatory Bowel Disease.Gastroenterology & hepatology · 2016Article
- Reproductive Planning and Contraception for Women with Inflammatory Bowel Diseases.Inflammatory bowel diseases · 2016Review
- Sex-Specific Issues in Inflammatory Bowel Disease.Gastroenterology & hepatology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundWomen with inflammatory bowel diseases (IBD) commonly report an increase in their IBD symptoms related to their menstrual cycle. Hormonal contraceptives are safe for women with IBD and frequently used for reproductive planning, but data are lacking on their effect on IBD-related symptoms.
methodsWe completed a cross-sectional phone survey of 129 women (31% response rate), aged 18 to 45 years, with IBD in an academic practice between March and November 2013. An electronic database query identified eligible women, and we sent an opt-out letter before contact. Questions included demographics, medical and reproductive history, and current/previous contraceptive use. Women were asked if/how their menses affected IBD-related symptoms and if/how their contraceptive affected symptoms. We calculated descriptive statistics and made comparisons by Crohn's disease versus ulcerative colitis on Stata V11.
resultsParticipants were predominately white (85%) and college educated (97%), with a mean age of 34.2 (SD 6.2, range 19-45) years. Sixty percent had Crohn's disease, and 30% had IBD-related surgery previously. Half of the participants were parous, and 57% desired future pregnancy. Of the participants, 88% reported current or past hormonal contraceptive use and 60% noted cyclical IBD symptoms. Symptomatic improvement in cyclical IBD symptoms was reported by 19% of estrogen-based contraceptive users and 47% of levonorgestrel intrauterine device users. Only 5% of all hormonal method users reported symptomatic worsening.
conclusionsIn a subset of women with IBD, 20% of hormonal contraception users reported improved cyclical menstrual-related IBD symptoms. Health care providers should consider potential noncontraceptive benefits of hormonal contraception in women with cyclical IBD symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.