ArticlePloS one2014
Visceral adiposity index may be a surrogate marker for the assessment of the effects of obesity on arterial stiffness.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 73 citations in OpenAlex.
- Association of emerging anthropometric ratios with arterial stiffness risk measured by pulse wave velocity: insights from a middle-eastern population.Journal of health, population, and nutrition · 2026Article
- Arterial stiffness, high fasting glucose, and fatty liver as risk factors for visceral obesity in middle-aged Chinese individuals: a cross-sectional study.Endocrine journal · 2025Article
- Association between visceral adiposity index, lipid accumulation product and type 2 diabetes mellitus in US adults with hypertension: a cross-sectional analysis of NHANES from 2005 to 2018.BMC endocrine disorders · 2024Article
- Evaluating the Association of Anthropometric Indices With Total Cholesterol in a Large Population Using Data Mining Algorithms.Journal of clinical laboratory analysis · 2024Article
- Chinese visceral adipose index is more closely associated with risk of arterial stiffness than traditional obesity indicators: a cohort study.Diabetology & metabolic syndrome · 2024Article
- Neuro-Adipokine Crosstalk in Alzheimer's Disease.International journal of molecular sciences · 2024Review
- Age-adjusted visceral adiposity index (VAI) is superior to VAI for predicting mortality among US adults: an analysis of the NHANES 2011-2014.Aging clinical and experimental research · 2024Article
- Gender Differences in the Predictive Value of Obesity Indices for Insulin Resistance in Adult Mexican Individuals.Endocrine, metabolic & immune disorders drug targets · 2024Article
- Association between visceral obesity and 10-year risk of first atherosclerotic cardiovascular diseases events among American adults: National Health and Nutrition Examination Survey.Frontiers in cardiovascular medicine · 2023Article
- Evaluation of Arterial Stiffness and Its Relation to Innovative Anthropometric Indices in Persian Adults.International journal of hypertension · 2023Article
- Use of the Visceral Adiposity Index as an Indicator of Chronic Kidney Disease in Older Adults: Comparison with Body Mass Index.Journal of clinical medicine · 2022Article
- Visceral adiposity index and sex differences in relation to peripheral artery disease in normal-weight adults with hypertension.Biology of sex differences · 2022Article
- Association between Visceral Adipose Tissue Metabolism and Alzheimer's Disease Pathology.Metabolites · 2022Article
- Association between fibrinogen/albumin ratio and arterial stiffness in patients with type 2 diabetes: A cross-sectional study.Frontiers in pharmacology · 2022Article
- Visceral adiposity index is associated with arterial stiffness in hypertensive adults with normal-weight: the china H-type hypertension registry study.Nutrition & metabolism · 2021Article
- Association between organ damage and visceral adiposity index in community-dwelling elderly Chinese population: the Northern Shanghai Study.Aging clinical and experimental research · 2021Article
- Visceral adiposity index is associated with silent brain infarct in a healthy population.Scientific reports · 2020Article
- Association between non-obesity and health state among young Japanese male university students.Journal of physical therapy science · 2020Article
- Potential Role of New Anthropometric Parameters in Childhood Obesity with or Without Metabolic Syndrome.Open access Macedonian journal of medical sciences · 2019Article
- Visceral adipose accumulation increased the risk of hyperuricemia among middle-aged and elderly adults: a population-based study.Journal of translational medicine · 2019Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe relationship between obesity and cardiovascular disease (CVD) remains unclear. This study aims to describe the relationship between arterial stiffness and obesity in order to investigate the effects of obesity on CVD.
methodsWe collected data from 5,158 individuals over 40 years of age from a cross-sectional study in Nanjing, China. Anthropometric, demographic, hemodynamic measurements and arterial stiffness measured through brachial-ankle pulse wave velocity (baPWV) were obtained. Subjects were grouped by body mass index (BMI), waist circumference (WC) and visceral adiposity index (VAI), a sex-specific index based on BMI, WC, triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C).
resultsThe multivariate regression analysis revealed a negative but weak effect of BMI (β = -0.047, P<0.001) on baPWV, but failed to demonstrate any significant effect of WC on baPWV while VAI was a positive independent indicator of baPWV (β = 0.023, P = 0.022). The unadjusted baPWV significantly increased across groups with higher obesity categories (P<0.01). Although the positive association was lost after adjustments for confounding factors in the BMI or WC categories (P>0.05), it was still obtained between baPWV and VAI quartile (P<0.01). No differences were observed among the metabolically healthy groups or the metabolically abnormal groups in the BMI and WC categories (P>0.05). However, baPWV significantly increased across groups with higher VAI categories even in the same metabolic category (P<0.01).
conclusionsThis study supports the concept of heterogeneity of metabolic status among individuals within the same obesity range. Obese individuals are at an increased risk of arterial stiffness regardless of their metabolic conditions. VAI may be a surrogate marker for the assessment of obesity and the effects of obesity on arterial stiffness.
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