ArticlePloS one2014
Enhanced cell adhesion and alignment on micro-wavy patterned surfaces.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Vascular endothelial integration of multiple biophysical stimuli.Frontiers in cardiovascular medicine · 2026Article
- Improvement of cellular pattern organization and clarity through centrifugal force.Biomedical materials (Bristol, England) · 2025Article
- The time dependent influence of curvature and topography of biomaterials in the behavior of corneal endothelial cells.Frontiers in bioengineering and biotechnology · 2024Article
- Biomimetic approach to articular cartilage tissue engineering using carbon nanotube-coated and textured polydimethylsiloxane scaffolds.Annals of the New York Academy of Sciences · 2022Article
- Influence of Indium (III) Chloride on Human Dermal Fibroblast Cell Adhesion on Tantalum/Silicon Oxide Nano-Composites.Materials (Basel, Switzerland) · 2022Article
- Nano-Second Laser Interference Photoembossed Microstructures for Enhanced Cell Alignment.Polymers · 2021Article
- Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out.Nanomaterials (Basel, Switzerland) · 2021Article
- Article
- Fundamental Characteristics of Neuron Adhesion Revealed by Forced Peeling and Time-Dependent Healing.Biophysical journal · 2020Article
- Polydopamine and collagen coated micro-grated polydimethylsiloxane for human mesenchymal stem cell culture.Bioactive materials · 2019Article
- 4D anisotropic skeletal muscle tissue constructs fabricated by staircase effect strategy.Biofabrication · 2019Article
- 3D Printed, Microgroove Pattern-Driven Generation of Oriented Ligamentous Architectures.International journal of molecular sciences · 2017Article
- Biomechanical Characterization of Cardiomyocyte Using PDMS Pillar with Microgrooves.Sensors (Basel, Switzerland) · 2016Article
- Creating biomaterials with spatially organized functionality.Experimental biology and medicine (Maywood, N.J.) · 2016Review
- Generation of Customizable Micro-wavy Pattern through Grayscale Direct Image Lithography.Scientific reports · 2016Article
- Maximizing Fibroblast Adhesion on Protein-Coated Surfaces Using Microfluidic Cell Printing.RSC advances · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Various micropatterns have been fabricated and used to regulate cell adhesion, morphology and function. Micropatterns created by standard photolithography process are usually rectangular channels with sharp corners (microgrooves) which provide limited control over cells and are not favorable for cell-cell interaction and communication. This paper proposes a new micropattern with smooth wavy surfaces (micro-waves) to control the position and orientation of cells. To characterize cell growth and responses on the micro-patterned substrates, bovine aortic endothelial cells were seeded onto surfaces with micro-grooves and micro-waves for 24 h. As a result, the cells on the micro-wavy pattern appeared to have a lower death rate and better alignment compared to those on the micro-grooved pattern. In addition, flow-induced shear stress was applied to examine the adhesion strength of cells on the micro-wavy pattern. Results showed that cells adhered to the wavy surface displayed both improved alignment and adhesion strength compared to those on the flat surface. The combination of increased alignment, lower death rate and enhanced adhesion strength of cells on the micro-wavy patterns will offer advantages in potential applications for cell phenotype, proliferation and tissue engineering.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.