Evidence map›Paper›PMID 25105059›Full record

ArticleBacteriophage2014

Molecular basis of RNA polymerase promoter specificity switch revealed through studies of

Konstantin Severinov, Leonid Minakhin, Shun-Ichi Sekine, Anna Lopatina, Shigeyuki Yokoyama

Open access · hybridAbstract read
In one paragraph

Article in Bacteriophage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Natural diversity of CRISPR spacers of Thermus: evidence of local spacer acquisition and global spacer exchange.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 5 countries.

Konstantin SeverinovWaksman Institute; Rutgers; The State University of New Jersey; Piscataway, NJ USA ; St. Petersburg Polytechnical State University; St. Petersburg, Russia ; Skolkovo Institute of Science and Technology; Skolkovo, Russia.
Leonid MinakhinWaksman Institute; Rutgers; The State University of New Jersey; Piscataway, NJ USA.
Shun-Ichi SekineRIKEN Systems and Structural Biology Center; Tsurumi-ku, Yokohama Japan ; Division of Structural and Synthetic Biology; RIKEN Center for Life Science Technologies; Tsurumi-ku, Yokohama Japan.
Anna LopatinaSt. Petersburg Polytechnical State University; St. Petersburg, Russia ; Institutes of Gene Biology and Molecular Genetics; Russian Academy of Sciences; Moscow, Russia.
Shigeyuki YokoyamaRIKEN Systems and Structural Biology Center; Tsurumi-ku, Yokohama Japan ; RIKEN Structural Biology Laboratory; Tsurumi-ku, Yokohama Japan.
Ackerman Institute for the Family · USRussian Academy of Sciences · RUSkolkovo Institute of Science and Technology · RUSynthetic Biologics (United States) · USTsurumi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transcription initiation is the central point of gene expression regulation. Understanding of molecular mechanism of transcription regulation requires, ultimately, the structural understanding of consequences of transcription factors binding to DNA-dependent RNA polymerase (RNAP), the enzyme of transcription. We recently determined a structure of a complex between transcription factor gp39 encoded by a

Indexed as

bacterial RNA polymerasebacteriophageinhibitorsigma factortranscription regulation

Identifiers

PMID25105059
PMCPMC4124052
OpenAlexW1995401304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.