ArticleJournal of ophthalmology2014
Big bubble deep anterior lamellar keratoplasty for management of deep fungal keratitis.
Article in Journal of ophthalmology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 34 citations in OpenAlex.
- Fungal keratitis in Germany : Diagnostics, conservative and microsurgical treatment.Die Ophthalmologie · 2026Review
- [Fungal keratitis in Germany : Diagnostics, conservative and microsurgical treatment].Die Ophthalmologie · 2025Review
- Outcomes of Post-Keratoplasty Microbial Keratitis: A 16-Year Analysis.Journal of clinical medicine · 2025Article
- Post-Keratoplasty Microbial Keratitis in the Era of Lamellar Transplants-A Comprehensive Review.Journal of clinical medicine · 2024Review
- Comparison of therapeutic effects between big-bubble deep anterior lamellar keratoplasty and penetrating keratoplasty for medically unresponsive Acanthamoeba keratitis.BMC infectious diseases · 2024Article
- Fungal Keratitis: Diagnosis, Management, and Recent Advances.Clinical ophthalmology (Auckland, N.Z.) · 2024Review
- Characteristics of In Vitro Culture and In Vivo Confocal Microscopy in Patients with Fungal Keratitis in a Tertiary Referral Hospital in Central China.Microorganisms · 2023Article
- Outcomes of Severe Fungal Keratitis Using in vivo Confocal Microscopy and Early Therapeutic Penetrating Keratoplasty.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Clinical application of a shape-preserving rapid corneal donor dehydrater.International journal of ophthalmology · 2022Article
- Article
- Endothelial Plaques as Sign of Hyphae Infiltration of Descemet's Membrane in Fungal Keratitis.Journal of ophthalmology · 2020Article
- Outcomes of therapeutic keratoplasty for severe infectious keratitis in Chongqing, a 16-year experience.Infection and drug resistance · 2019Article
- Clinical outcome after air-assisted manual deep anterior lamellar keratoplasty for fungal keratitis poorly responsive to medical treatment.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Etiology and failure analysis of anterior lamellar keratoplasty.International journal of ophthalmology · 2018Article
- Early deep anterior lamellar keratoplasty for fungal keratitis poorly responsive to medical treatment.Eye (London, England) · 2017Article
- Observational
- Surgical management of corneal infections.Current opinion in ophthalmology · 2016Review
- Review of clinical and basic approaches of fungal keratitis.International journal of ophthalmology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective. To evaluate the therapeutic effect of big bubble deep anterior lamellar keratoplasty (DALK) in patients with deep fungal keratitis. Methods.Consecutive patients who had DALK for deep fungal keratitis at Shandong Eye Hospital between July 2011 and December 2012 were included. In all patients, the infiltration depth was more than 4/5ths of the corneal thickness. DALK surgery was performed with bare Descemet membrane (DM) using the big bubble technique. Corrected distance visual acuity (CDVA), graft status, and intraoperative and postoperative complications were monitored. Results. Big bubble DALK was performed in 23 patients (23 eyes). Intraoperative perforation of the DM occurred in two eyes (8.7%) during stromal dissection. The patients received lamellar keratoplasty with an air bubble injected into the anterior chamber. Double anterior chamber formed in 3 eyes (13.0%). Mean CDVA of the patients without cataract, amblyopia, and fungal recurrence was improved from preoperative HM/20 cm-1.0 (LogMAR) to 0.23 ± 0.13 (LogMAR) at the last followup (P < 0.01). Fungal recurrence was found in two patients (8.7%). Corneal stromal graft rejection was noted in one patient (4.3%). Conclusions. DALK using the big bubble technique seems to be effective and safe in the treatment of deep fungal keratitis unresponsive to medication.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.