Evidence map›Paper›PMID 25104952›Full record

ReviewFrontiers in microbiology2014

Maternal and congenital toxoplasmosis, currently available and novel therapies in horizon.

Helieh S Oz

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Seroprevalence ofSouthern African journal of infectious diseases · 2020
    Article
  6. Biogenic Silver Nanoparticles Can ControlFrontiers in microbiology · 2020
    Article
  7. CNS Macrophages and Infant Infections.Frontiers in immunology · 2020
    Review
  8. Fetomaternal and Pediatric Toxoplasmosis.Journal of pediatric infectious diseases · 2017
    Article
  9. Review
  10. Congenital hearing loss.Nature reviews. Disease primers · 2017
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Isoprenoid metabolism in apicomplexan parasites.Current clinical microbiology reports · 2014
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Helieh S OzDepartment of Medicine, University of Kentucky Medical Center Lexington, KY, USA.
University of Kentucky · US

Funding

A Novel Murine Model of Chronic Inflammatory PeriodontitusR03DE019177 · NIDCR · UNIVERSITY OF KENTUCKY · PI OZ, HELIEH S · 2009 to 2010
$223k
NIDCR NIH HHS R03 DE019177
6 · The paper itself

Abstract

Over one billion people worldwide are predicted to harbor Toxoplasma infection frequently with unknown lifelong health consequences. Toxoplasmosis is an important cause of foodborne, inflammatory illnesses, as well as congenital abnormalities. Ubiquitous Toxoplasma has a unique tropism for central nervous system with a mind-bugging effect and is transmitted sexually through semen. Currently available therapies are ineffective for persistent chronic disease and congenital toxoplasmosis or have severe side effects which may result in life-threatening complications. There is an urgent need for safe and effective therapies to eliminate or treat this cosmopolitan infectious and inflammatory disease. This investigation discusses pathogenesis of maternal and congenital toxoplasmosis, the currently available therapies in practice, and the experimental therapeutic modalities for promising future trials.

Indexed as

atovaquonecongenital toxoplasmosisdiclazurilfetal maternalmind alterationsexual transmission

Identifiers

PMID25104952
PMCPMC4109466
OpenAlexW2108562728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.