Evidence map›Paper›PMID 25104285›Full record

ArticleAJNR. American journal of neuroradiology2014

Low-tube-voltage 80-kVp neck CT: evaluation of diagnostic accuracy and interobserver agreement.

J L Wichmann, J Kraft, E-M Nöske, B Bodelle, I Burck, J-E Scholtz, C Frellesen, J Wagenblast, J M Kerl, R W Bauer and 3 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Dual-Energy CT in Head and Neck Imaging.Current radiology reports · 2017
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Optimized imaging of the midface and orbits.GMS current topics in otorhinolaryngology, head and neck surgery · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

J L WichmannFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.) docwichmann@gmail.com.
J KraftFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
E-M NöskeFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
B BodelleFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
I BurckFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
J-E ScholtzFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
C FrellesenFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
J WagenblastOtolaryngology, Head and Neck Surgery (J.W.), University Hospital Frankfurt, Frankfurt, Germany.
J M KerlFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
R W BauerFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
T LehnertFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
T J VoglFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
B SchulzFrom the Departments of Diagnostic and Interventional Radiology (J.L.W., J.K., E.-M.N., B.B., I.B., J.-E.S, C.F., J.M.K., R.W.B., T.L., T.J.V., B.S.).
Society of Interventional Radiology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeLow-tube-voltage acquisition has been shown to facilitate substantial dose savings for neck CT with similar image contrast compared with standard 120-kVp acquisition. However, its potential for the detection of neck pathologies is uncertain. Our aim was to evaluate the effects of low-tube-voltage 80-kV(peak) acquisitions for neck CT on diagnostic accuracy and interobserver agreement. MATERIALS AND

methodsThree radiologists individually analyzed 80-kVp and linearly blended 120-kVp image series of 170 patients with a variety of pathologies who underwent dual-energy neck CT. Reviewers were unblinded to the clinical indication for CT but were otherwise blinded to any other data or images and were asked to state a final main diagnosis. Findings were compared with medical record charts, CT reports, and pathology results. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated for each observer. Interobserver agreement was evaluated by using intraclass correlation coefficients.

resultsDiagnoses were grouped as squamous cell carcinoma-related (n = 107, presence/absence of primary/recurrent squamous cell carcinoma), lymphoma-related (n = 40, presence/absence of primary/recurrent lymphoma), and benign (n = 23, eg, abscess). Cumulative sensitivity, specificity, positive predictive value, and negative predictive value for 80-kVp and blended 120-kVp images were 94.8%, 93.0%, 95.9%, and 91.1%, respectively. Results were also consistently high for squamous cell carcinoma-related (94.8%/95.3%, 89.1%/89.1%, 94.3%/94.4%, 90.1%/91.0%) and lymphoma-related (95.0%, 100.0%, 100.0%, 95.2%) 80-kVp/120-kVp image series. Global interobserver agreement was almost perfect (intraclass correlation coefficient, 0.82, 0.80; 95% CI, 0.76-0.74, 0.86-0.85). Calculated dose-length product was reduced by 48% with 80-kVp acquisitions compared with the standard 120-kVp scans (135.5 versus 282.2 mGy × cm).

conclusionsLow-tube-voltage 80-kVp CT of the neck provides sufficient image quality with high diagnostic accuracy in routine clinical practice and has the potential to substantially decrease radiation exposure.

Indexed as

Observer VariationRadiation DosageAbscessAdolescentAdultAgedAged, 80 and overCarcinoma, Squamous CellFemaleHead and Neck NeoplasmsHumansLymphomaMaleMiddle AgedNeckRadiography, Dual-Energy Scanned Projection

Identifiers

PMID25104285
PMCPMC7965325
OpenAlexW2324835527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.