Evidence map›Paper›PMID 25104051›Full record

ArticleGlobal public health2014

The ethics of health systems research in low- and middle-income countries: a call to action.

Adnan A Hyder, Bridget Pratt, Joseph Ali, Nancy Kass, Nelson Sewankambo

Abstract read
In one paragraph

Article in Global public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. [Variability and discrepancies between Ethics Committees in the evaluation of academic research projects]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Adnan A Hydera Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.
Bridget Pratt
Joseph Ali
Nancy Kass
Nelson Sewankambo

Funding

The Addis Ababa University-Johns Hopkins University Research Ethics Training Program in Ethiopia (AAU-JHU RETP)R25TW001604 · FIC · JOHNS HOPKINS UNIVERSITY · PI Adamu Addissie, Joseph Ali · 2000 to 2026
$6.4M
JHU-Afghanistan-Pakistan Collaborative Trauma and Injury Research TrainingD43TW007292 · FIC · JOHNS HOPKINS UNIVERSITY · PI Nadeem Ullah Khan, Junaid Abdul Razzak · 2005 to 2026
$4.7M
FIC NIH HHS D43 TW007292FIC NIH HHS R25 TW 001604FIC NIH HHS R25 TW001604
6 · The paper itself

Abstract

The increasing conduct of health systems research (HSR) in low- and middle-income countries (LMICs) has not been matched by concurrent work to clarify the field's ethical dimensions. To begin to address this gap, a two-day workshop on the ethics of HSR in LMICs was convened at Johns Hopkins University in June 2013. Participants included health systems researchers, philosophers, lawyers, bioethicists and institutional review board members from Botswana, Uganda, the UK, USA and Zambia. Based on discussions from the workshop, the paper affirms that, while HSR in LMICs raises ethical issues in relation to constructs (i.e. consent, risk, equipoise) common to international clinical research, the nature of the issues that arise often differ between the two fields. Three salient features of HSR and the ethical considerations associated with each of them in LMICs are described to demonstrate this point. Recommendations for institutional review boards' oversight of HSR in LMICs are presented. Finally, a call is made for further action to develop thinking and guidance around the ethics of HSR in resource-poor settings.

Indexed as

Developing CountriesCongresses as TopicEthics Committees, ResearchHealth Services ResearchHumansdeveloping countriesethicshealth systems researchIRB oversight

Identifiers

PMID25104051
PMCPMC4198578

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.