ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2014
A prospective study of physical activity and breast cancer incidence in African-American women.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.British journal of sports medicine · 2023Pooled it
- Sedentary work and breast cancer risk: A systematic review and meta-analysis.Journal of occupational health · 2021Pooled it
- Modelling the potential health and economic benefits of reducing population sitting time in Australia.The international journal of behavioral nutrition and physical activity · 2022Trial
- International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024Article
- mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women's circle of health study.Breast cancer research and treatment · 2023Article
- Physical activity from menarche-to-first pregnancy and risk of breast cancer: the California teachers study.Cancer causes & control : CCC · 2022Article
- Place Is Power: Investing in Communities as a Systemic Leverage Point to Reduce Breast Cancer Disparities by Race.International journal of environmental research and public health · 2022Review
- The Premenopausal Breast Cancer Collaboration: A Pooling Project of Studies Participating in the National Cancer Institute Cohort Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Review
- Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence.The Lancet. Oncology · 2017Review
- Differential Patterns of Risk Factors for Early-Onset Breast Cancer by ER Status in African American Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2017Article
- Adherence to diet, physical activity and body weight recommendations and breast cancer incidence in the Black Women's Health Study.International journal of cancer · 2016Article
- Sedentary time and breast cancer incidence in African American women.Cancer causes & control : CCC · 2016Article
- Vigorous physical activity and risk of breast cancer in the African American breast cancer epidemiology and risk consortium.Breast cancer research and treatment · 2016Article
- Psychosocial Variables Related to Why Women are Less Active than Men and Related Health Implications.Clinical medicine insights. Women's health · 2016Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundPhysical activity has been associated with reduced risk of breast cancer. Evidence on the association in African Americans is limited.
methodsWith prospective data from the Black Women's Health Study, we assessed vigorous exercise and walking in relation to incidence of invasive breast cancer overall (n = 1,364), estrogen receptor-positive (ER(+), n = 688) cancer, and estrogen receptor-negative (ER(-), n = 405) cancer, based on 307,672 person-years of follow-up of 44,708 African-American women ages 30 years or older at enrollment. Cox proportional hazards models estimated incidence rate ratios (IRR) and 95% confidence intervals (CI).
resultsVigorous exercise at baseline was inversely associated with overall breast cancer incidence (Ptrend = 0.05): the IRR for ≥7 h/wk relative to <1 h/wk was 0.74 (95% CI, 0.57-0.96). The association did not differ by ER status. Brisk walking for ≥7 h/wk was associated with a reduction similar to that for vigorous exercise. Vigorous exercise at the age of 30 years, 21 years, or in high school was not associated with breast cancer incidence. Sitting for long periods at work or watching TV was not significantly associated with breast cancer incidence.
conclusionHigh levels of vigorous exercise or brisk walking may be associated with a reduction in incidence of breast cancer in African-American women. IMPACT: These results provide informative data on a potential modifiable risk factor, exercise, for breast cancer in African-American women.
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