Evidence map›Paper›PMID 25103787›Full record

ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2015

The effect of increased intracranial pressure on vestibular evoked myogenic potentials in superior canal dehiscence syndrome.

Kristen L Janky, M Geraldine Zuniga, Michael C Schubert, John P Carey

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Kristen L JankyJohns Hopkins University, Otolaryngology - Head and Neck Surgery, Baltimore, MD 21287-0910, USA; Boys Town National Research Hospital, Department of Audiology, Omaha, NE 68131, USA. Electronic address: kristen.janky@boystown.org.
M Geraldine ZunigaJohns Hopkins University, Otolaryngology - Head and Neck Surgery, Baltimore, MD 21287-0910, USA; Department of Otolaryngology Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Michael C SchubertJohns Hopkins University, Otolaryngology - Head and Neck Surgery, Baltimore, MD 21287-0910, USA; Johns Hopkins University, Physical Medicine and Rehabilitation, Baltimore, MD 21287-0910, USA.
John P CareyJohns Hopkins University, Otolaryngology - Head and Neck Surgery, Baltimore, MD 21287-0910, USA.
Boys Town National Research Hospital · USJohns Hopkins Medicine · USJohns Hopkins University · USVanderbilt University · US

Funding

The Impact of Mild Hearing Loss on Auditory Perception in Complex EnvironmentsP20GM109023 · NIGMS · FATHER FLANAGAN'S BOYS' HOME · PI LANCASTER, HOPE SPARKS · 2014 to 2023
$23.4M
Training Program in Hearing and BalanceT32DC000023 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CULLEN, KATHLEEN E · 1989 to 2025
$8.7M
Evalution of Vestibular Function in Meniere's DiseaseR01DC005040 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI CAREY, JOHN PATRICK · 2002 to 2009
$2.6M
VOR adaptation/utility of saccades as rehab strategiesK23DC007926 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI SCHUBERT, MICHAEL C · 2005 to 2008
$538k
NIDCD NIH HHS K23 DC007926NIDCD NIH HHS R01 DC005040NIDCD NIH HHS T32 DC000023NIDCD NIH HHS T32DC000023NIGMS NIH HHS P20 GM109023PHS HHS K23-007926
6 · The paper itself

Abstract

objectiveTo determine if vestibular evoked myogenic potential (VEMP) responses change during inversion in patients with superior canal dehiscence syndrome (SCDS) compared to controls.

methodsSixteen subjects with SCDS (mean: 43, range 30-57 years) and 15 age-matched, healthy subjects (mean: 41, range 22-57 years) completed cervical VEMP (cVEMP) in response to air conduction click stimuli and ocular VEMP (oVEMP) in response to air conduction 500 Hz tone burst stimuli and midline tap stimulation. All VEMP testing was completed in semi-recumbent and inverted conditions.

resultsSCDS ears demonstrated significantly larger oVEMP peak-to-peak amplitudes in comparison to normal ears in semi-recumbency. While corrected cVEMP peak-to-peak amplitudes were larger in SCDS ears; this did not reach significance in our sample. Overall, there was not a differential change in o- or cVEMP amplitude with inversion between SCDS and normal subjects.

conclusionsPostural-induced changes in o- and cVEMP responses were measured in the steady state regardless of whether the labyrinth was intact or dehiscent. SIGNIFICANCE: VEMP responses are blunted during inversion. Although steady-state measurements of VEMPs during inversion do not increase diagnostic accuracy for SCDS, the findings suggest that inversion may provide more general insights into the equilibration of pressures between intracranial and intralabyrinthine fluids.

Indexed as

Acoustic StimulationAdultFemaleHumansIntracranial PressureMaleMiddle AgedSemicircular CanalsSyndromeVestibular DiseasesVestibular Evoked Myogenic PotentialsVestibular Function TestsVestibule, LabyrinthYoung AdultIntracranial pressureSuperior canal dehiscenceVestibular evoked myogenic potential

Identifiers

PMID25103787
PMCPMC4297745
OpenAlexW1963813485

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.