Evidence map›Paper›PMID 25103606›Full record

SynthesisJournal of cancer survivorship : research and practice2014

Fertility and parenthood issues in young female cancer patients--a systematic review.

Aleksandra Sobota, Gozde Ozakinci

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Management of Primary Ovarian Insufficiency Symptoms in Survivors of Childhood and Adolescent Cancer.Journal of the National Comprehensive Cancer Network : JNCCN · 2018
    Pooled it
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  16. Developing a post-treatment survivorship care plan to help breast cancer survivors understand their fertility.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
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  18. Reproductive Patterns Among Childhood and Adolescent Cancer Survivors in Sweden: A Population-Based Matched-Cohort Study.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aleksandra SobotaSchool of Medicine, Biological and Medical Sciences Building, University of St Andrews, North Haugh, St Andrews, Fife, KY16 9TF, Scotland, UK, as297@st-andrews.ac.uk.
Gozde Ozakinci
University of St Andrews · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFor young women who were diagnosed with cancer prior to having children, reproductive potential might affect the quality of life (QoL). This systematic review looks at fertility issues in young female cancer patients, focusing on their influence on psychological well-being, specific fertility-related interventions and reproductive decisions.

methodsThirteen medical and social science databases were searched for relevant articles up to December 2012, according to PRISMA guidelines. Twenty-six articles meeting the eligibility criteria were included in the review, along with 5 additional papers that missed the inclusion criteria narrowly. Narrative synthesis was used to analyse the studies.

resultsDepression, anxiety and quality of life (QoL) seemed to be related to the perceptions of reproductive issues rather than to the fertility status based on the type of treatment received. Fertility-related interventions improved patients' QoL, decisional regret, and decisional conflict. Finally, cancer influenced women's reproductive decisions. Pursuing pregnancy was affected mainly by worries about child's and mother's health. Decisions about treatment were influenced by the wish to preserve fertility. The generalisability of these results might be undermined by small sample sizes and homogeneity of participants within and across the studies. Inferences about causality of associations are problematic due to predominantly cross-sectional design. IMPLICATIONS FOR CANCER SURVIVORS: The existing literature gives preliminary insight into the importance of fertility for young women diagnosed with cancer. However, more research is needed in order to offer patients comprehensive care.

Indexed as

FemaleFertilityHumansNeoplasmsSurvivors

Identifiers

PMID25103606
OpenAlexW1998835407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.