ArticleThe Permanente journal2014
Prediabetes and lifestyle modification: time to prevent a preventable disease.
Article in The Permanente journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
127 citing papers in PubMed, 10 syntheses or guidelines pooled it, 252 citations in OpenAlex.
- The Effect of Diabetes on Outcomes of Non-Surgical Periodontal Therapy: A Systematic Review With a Meta-Analysis and Trial Sequential Analysis.International journal of dental hygiene · 2026Pooled it
- Prediabetes and the risk of incident chronic kidney disease in adults: A systematic review and meta-analysis.Biomolecules & biomedicine · 2026Pooled it
- The association between prediabetes and obstructive sleep apnea syndrome: a meta-analysis.Frontiers in endocrinology · 2026Pooled it
- Prediabetes in adult Saudis: a systematic review & meta-analysis of prevalence studies (2000-2024).PeerJ · 2025Pooled it
- Motivational Interviewing in Pediatric Obesity: A Meta-analysis of the Effects on Behavioral Outcomes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2023Pooled it
- Knowledge, attitude, and practice toward pre-diabetes among the public, patients with pre-diabetes and healthcare professionals: a systematic review.BMJ open diabetes research & care · 2023Pooled it
- Effect of brown seaweed on plasma glucose in healthy, at-risk, and type 2 diabetic individuals: systematic review and meta-analysis.Nutrition reviews · 2022Pooled it
- The risk of tooth loss in patients with diabetes: A systematic review and meta-analysis.International journal of dental hygiene · 2022Pooled it
- Pooled it
- The Influence of Probiotics Consumption on Management of Prediabetic State: A Systematic Review of Clinical Trials.International journal of clinical practice · 2022Pooled it
- Totum-63, a plant-based polyphenol-rich extract, in prediabetes or early-stage type 2 diabetes: an international, multicenter, randomized controlled trial.Nature communications · 2026Trial
- Effects of a Text Message-Based Lifestyle Intervention on HbA1c and Health Behaviors in Older Adults with Prediabetes.Nutrients · 2026Trial
- Trial
- Effects of a diverse prebiotic fibre supplement on HbA1c, insulin sensitivity and inflammatory biomarkers in pre-diabetes: a pilot placebo-controlled randomised clinical trial.The British journal of nutrition · 2024Trial
- Lifestyle intervention reduces risk score for cardiovascular mortality in company employees with pre-diabetes or diabetes mellitus - A secondary analysis of the PreFord randomized controlled trial with 3 years of follow-up.Frontiers in endocrinology · 2023Trial
- Effects of Totum-63 on glucose homeostasis and postprandial glycemia: a translational study.American journal of physiology. Endocrinology and metabolism · 2021Trial
- Alendronate improves fasting plasma glucose and insulin sensitivity, and decreases insulin resistance in prediabetic osteopenic postmenopausal women: A randomized triple-blind clinical trial.Journal of diabetes investigation · 2019Trial
- Trial
- Trial
- Identification of Frailty Subtypes in African American Adults With and Without Type 2 Diabetes: A Latent Class Analysis From the Jackson Heart Study.Diabetes, obesity & metabolism · 2026Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
More than 100 million Americans have prediabetes or diabetes. Prediabetes is a condition in which individuals have blood glucose levels higher than normal but not high enough to be classified as diabetes. People with prediabetes have an increased risk of Type 2 diabetes. An estimated 34% of adults have prediabetes. Prediabetes is now recognized as a reversible condition that increases an individual's risk for development of diabetes. Lifestyle risk factors for prediabetes include overweight and physical inactivity.Increasing awareness and risk stratification of individuals with prediabetes may help physicians understand potential interventions that may help decrease the percentage of patients in their panels in whom diabetes develops. If untreated, 37% of the individuals with prediabetes may have diabetes in 4 years. Lifestyle intervention may decrease the percentage of prediabetic patients in whom diabetes develops to 20%.Long-term data also suggest that lifestyle intervention may decrease the risk of prediabetes progressing to diabetes for as long as 10 years. To prevent 1 case of diabetes during a 3-year period, 6.9 persons would have to participate in the lifestyle intervention program. In addition, recent data suggest that the difference in direct and indirect costs to care for a patient with prediabetes vs a patient with diabetes may be as much as $7000 per year. Investment in a diabetes prevention program now may have a substantial return on investment in the future and help prevent a preventable disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.