Observational studyArchives of physical medicine and rehabilitation2014
Comorbidity and functional mobility in persons with Parkinson disease.
Observational study in Archives of physical medicine and rehabilitation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Association between Comorbidity Indices and Functional Autonomy in Individuals with Cognitive Impairment: A Systematic Review.The journal of prevention of Alzheimer's disease · 2024Pooled it
- Self-Reported Visual Complaints in People with Parkinson's Disease: A Systematic Review.Journal of Parkinson's disease · 2022Pooled it
- Effect of Aerobic Exercise on Cardiopulmonary Responses and Predictors of Change in Individuals With Parkinson's Disease.Archives of physical medicine and rehabilitation · 2021Trial
- Effects of 2 Years of Exercise on Gait Impairment in People With Parkinson Disease: The PRET-PD Randomized Trial.Journal of neurologic physical therapy : JNPT · 2017Trial
- Relative contribution of comorbid diseases to health-related quality of life in patients with Parkinson's disease.Journal of patient-reported outcomes · 2024Article
- The effects of medical comorbidity, cognition, and age on patient-reported outcomes in Parkinson's disease.Parkinsonism & related disorders · 2023Article
- Accumulation of Chronic Disease Among Survivors of Childhood Cancer Predicts Early Mortality.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023Article
- Factors influencing mobility among people post-surgery for hip fractures: A cross-sectional study.Belitung nursing journal · 2023Article
- Patient Safety in a Box: Implementation and Evaluation of the Emergency Box in Geriatric and Parkinson Patients.Journal of clinical medicine · 2021Article
- Longitudinal, Interdisciplinary Home Visits Versus Usual Care for Homebound People With Advanced Parkinson Disease: Protocol for a Controlled Trial.JMIR research protocols · 2021Article
- Is Dysphagia in Older Patients with Parkinson's Disease Associated With Sarcopenia ?The journal of nutrition, health & aging · 2021Article
- Detraining Effect on Pulmonary and Cardiovascular Autonomic Function and Functional Outcomes in Patients With Parkinson's Disease After Respiratory Muscle Training: An 18-Month Follow-Up Study.Frontiers in neurology · 2021Article
- QTc Interval Prolongation with Therapies Used to Treat Patients with Parkinson's Disease Psychosis: A Narrative Review.Neuropsychiatric disease and treatment · 2021Review
- Simultaneously Improved Pulmonary and Cardiovascular Autonomic Function and Short-Term Functional Outcomes in Patients with Parkinson's Disease after Respiratory Muscle Training.Journal of clinical medicine · 2020Article
- A physical therapy decision-making tool for stratifying persons with Parkinson's disease into community exercise classes.Neurodegenerative disease management · 2019Article
- Article
- Interdisciplinary Home Visits for Individuals with Advanced Parkinson's Disease and Related Disorders.Journal of the American Geriatrics Society · 2018Article
- Association of Strength and Physical Functions in People with Parkinson's Disease.Neuroscience journal · 2018Article
- Co-morbidity and polypharmacy in Parkinson's disease: insights from a large Scottish primary care database.BMC neurology · 2017Article
- Medication use and falls: Applying Beers criteria to medication review in Parkinson's disease.SAGE open medicine · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo report the frequency, severity, and types of comorbidities in people with Parkinson disease (PD) using a validated self-report comorbidity screening tool, and to determine the relationship between comorbidity and functional mobility.
designA secondary analysis and cross-sectional observational study design.
settingUniversity hospital; outpatient balance disorders laboratory.
participantsPersons with mild to moderate idiopathic PD (N=76).
interventionNot applicable.
main outcome measuresThe Cumulative Illness Rating Scale-Geriatric (CIRS-G) and a comprehensive mobility assessment including gait (distance walked in 3 min), balance (mini-Balance Evaluation Systems Test), and physical function (Physical Performance Test).
resultsAll participants reported comorbidities in addition to their diagnosed PD. The average ± SD number of comorbidities was 6.96 ± 2.0 (range, 2-11), and the total CIRS-G score ± SD was 12.7 ± 4.8. The most commonly reported organ systems with comorbidity were eyes and ears (89%), psychiatric (68%), musculoskeletal (64%), lower gastrointestinal (62%), respiratory (60.5%), upper gastrointestinal (59.2%), and genitourinary (53.9%). The total CIRS-G score was significantly related to functional mobility: gait (r=-.53, P=.0001), balance (r=-.43, P=.0003), and physical performance (r=-.36, P=.0041). Of the original 14 organ systems measured, there were 7 systems that, when combined, best predicted gait performance, 6 systems combined that best predicted balance performance, and 4 systems combined that predicted functional performance.
conclusionsThis study reports a high frequency of multiple medical system comorbidity in people with mild to moderate PD. Furthermore, comorbidity scores were associated with mobility disability: gait, balance, and physical function. Early intervention is important to delay mobility disability in PD, and we recommend that people with PD found to have comorbidities should be screened for balance and gait deficits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.