ArticleJournal of perinatology : official journal of the California Perinatal Association2015
Inhaled bronchodilator use for infants with bronchopulmonary dysplasia.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Inhaled bronchodilators for the prevention and treatment of chronic lung disease in preterm infants.The Cochrane database of systematic reviews · 2024Pooled it
- Pooled it
- A quality improvement initiative to reduce excess inhaled therapy use in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Current and Emerging Therapies for Prevention and Treatment of Bronchopulmonary Dysplasia in Preterm Infants.Paediatric drugs · 2025Review
- Comprehensive pulmonary function analysis identifies predominant obstructive phenotype in former premature infants around one year of age.Pediatric pulmonology · 2024Article
- Validity and reliability of the behavioral signs of respiratory instability (BSRI) © scale during activity for infants with bronchopulmonary dysplasia.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Pharyngeal biorhythms during oral milk challenge in high-risk infants: Do they predict chronic tube feeding?Neurogastroenterology and motility · 2023Article
- Prospective Risk Stratification Identifies Healthcare Utilization Associated with Home Oxygen Therapy for Infants with Bronchopulmonary Dysplasia.The Journal of pediatrics · 2022Article
- Imaging in neonatal respiratory disease.Paediatric respiratory reviews · 2022Review
- Bronchodilator responsiveness and dysanapsis in bronchopulmonary dysplasia.ERJ open research · 2022Article
- Inhaled Pharmacotherapy for Neonates: A Narrative Review.Turkish archives of pediatrics · 2022Article
- Pharmacotherapy in Bronchopulmonary Dysplasia: What Is the Evidence?Frontiers in pediatrics · 2022Review
- Established severe BPD: is there a way out? Change of ventilatory paradigms.Pediatric research · 2021Review
- Optimizing respiratory management in preterm infants: a review of adjuvant pharmacotherapies.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Low-dose hyperoxia primes airways for fibrosis in mice after influenza A infection.American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Response to first dose of inhaled albuterol in mechanically ventilated preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Pharmacoepidemiology of Drug Exposure in Intubated and Non-Intubated Preterm Infants With Severe Bronchopulmonary Dysplasia.Frontiers in pharmacology · 2021Article
- An Update on the Prevention and Management of Bronchopulmonary Dysplasia.Pediatric health, medicine and therapeutics · 2021Review
- Inhaled bronchodilator exposure in the management of bronchopulmonary dysplasia in hospitalized infants.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Bronchopulmonary Dysplasia: Then, Now, and Next.Pediatric allergy, immunology, and pulmonology · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo identify factors associated with bronchodilator administration to infants with bronchopulmonary dysplasia (BPD) and evaluate inter-institutional prescribing patterns. STUDY
designA retrospective cohort study of <29-week-gestation infants with evolving BPD defined at age 28 days within the Pediatric Health Information System database. Controlling for observed confounding with random-effects logistic regression, we determined demographic and clinical variables associated with bronchodilator use and evaluated between-hospital variation.
resultDuring the study period, 33% (N=469) of 1429 infants with BPD received bronchodilators. Lengthening mechanical ventilation duration increased the odds of receiving a bronchodilator (odds ratio 19.6 (11 to 34.8) at ⩾ 54 days). There was profound between-hospital variation in use, ranging from 0 to 81%.C ONCLUSION: Bronchodilators are frequently administered to infants with BPD at US children's hospitals with increasing use during the first hospital month. Increasing positive pressure exposure best predicts bronchodilator use. Frequency and treatment duration vary markedly by institution even after adjustment for confounding variables.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.