Evidence map›Paper›PMID 25101670›Full record

ReviewVirulence2014

The structure and retrotransposition mechanism of LTR-retrotransposons in the asexual yeast Candida albicans.

Lulu Zhang, Lan Yan, Jingchen Jiang, Yan Wang, Yuanying Jiang, Tianhua Yan, Yongbing Cao

Open access · goldAbstract readReview
In one paragraph

Review in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Endophytic entomopathogenic fungi: The next frontier in mycological biocontrol.World journal of microbiology & biotechnology · 2026
    Review
  2. Article
  3. Structural and Evolutionary Analysis ofInternational journal of molecular sciences · 2025
    Article
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  6. Review
  7. Article
  8. Review
  9. Annotation of Siberian Larch (Plants (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Lulu ZhangResearch and Develop Center of New Drug; School of Pharmacy; Second Military Medical University; Shanghai, PR China.
Lan YanResearch and Develop Center of New Drug; School of Pharmacy; Second Military Medical University; Shanghai, PR China.
Jingchen JiangDepartment of Pharmacology; School of Pharmacy; China Pharmaceutical University; Nanjing, PR China.
Yan WangResearch and Develop Center of New Drug; School of Pharmacy; Second Military Medical University; Shanghai, PR China.
Yuanying JiangResearch and Develop Center of New Drug; School of Pharmacy; Second Military Medical University; Shanghai, PR China.
Tianhua YanDepartment of Pharmacology; School of Pharmacy; China Pharmaceutical University; Nanjing, PR China.
Yongbing CaoResearch and Develop Center of New Drug; School of Pharmacy; Second Military Medical University; Shanghai, PR China.
Second Military Medical University · CNChina Pharmaceutical University · CNInternational Drug Development · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrotransposons constitute a major part of the genome in a number of eukaryotes. Long-terminal repeat (LTR) retrotransposons are one type of the retrotransposons. Candida albicans have 34 distinct LTR-retrotransposon families. They respectively belong to the Ty1/copia and Ty3/gypsy groups which have been extensively studied in the model yeast Saccharomyces cerevisiae. LTR-retrotransposons carry two LTRs flanking a long internal protein-coding domain, open reading frames. LTR-retrotransposons use RNA as intermediate to synthesize double-stranded DNA copies. In this article, we describe the structure feature, retrotransposition mechanism and the influence on organism diversity of LTR retrotransposons in C. albicans. We also discuss the relationship between pathogenicity and LTR retrotransposons in C. albicans.

Indexed as

Recombination, GeneticRetroelementsTerminal Repeat SequencesCandida albicansGenetic VariationRetroelementsCandida albicansLTR-retrotransposonsretrotransposition mechanismstructure featureTca

Identifiers

PMID25101670
PMCPMC4139406
OpenAlexW2033898946

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.