Evidence map›Paper›PMID 25101568›Full record

ArticleBritish journal of cancer2014

Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case-control EpiGEICAM study.

A Castelló, M Pollán, B Buijsse, A Ruiz, A M Casas, J M Baena-Cañada, V Lope, S Antolín, M Ramos, M Muñoz and 13 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 12 pooled it
13.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 12 syntheses or guidelines pooled it, 180 citations in OpenAlex.

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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 3 countries.

A Castelló1] Cancer Epidemiology Unit, National Center for Epidemiology, Instituto de Salud Carlos III, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [2] Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [3] Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.
M Pollán1] Cancer Epidemiology Unit, National Center for Epidemiology, Instituto de Salud Carlos III, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [2] Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Av/Monforte de Lemos, 5, 28029 Madrid, Spain.
B BuijsseDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.
A RuizMedical Oncology Unit, Instituto Valenciano de Oncología, C/Profesor Beltrán Baguena 19, 46009 Valencia, Spain.
A M CasasMedical Oncology Unit, Hospital Virgen del Rocío, Avenida Maneul Siurot S/N, 41013 Sevilla, Spain.
J M Baena-CañadaMedical Oncology Unit, Hospital Puerta del Mar, Avenida Ana De Viya 21, 11009 Cádiz, Spain.
V Lope1] Cancer Epidemiology Unit, National Center for Epidemiology, Instituto de Salud Carlos III, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [2] Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Av/Monforte de Lemos, 5, 28029 Madrid, Spain.
S AntolínMedical Oncology Unit, Complejo Hospitalario Universitario, Calle Xubias De Arriba, 84, 15006 A Coruña, Spain.
M RamosMedical Oncology Unit, Centro Oncológico de Galicia, Avenida Monsterrat S/N, 15009 A Coruña, Spain.
M MuñozMedical Oncology Unit, Hospital Clinic I Provincial de Barcelona, Calle Villaroel 170, 08036 Barcelona, Spain.
A LluchHematology-Oncology Department, Hospital Clínico Universitario de Valencia / INCLIVA, Universidad de Valencia, Avenida Blasco Ibáñez, 17, 46010 Valencia, Spain.
A de Juan-FerréMedical Oncology Unit, Hospital Marqués de Valdecilla, Avenida De Valdecilla S/N, 39008 Santander, Spain.
C JaraMedical Oncology Unit, Fundación Hospitalaria de Alcorcón, Calle Budapest 1, 28922 Alcorcón, Madrid, Spain.
M A JimenoSpanish Breast Cancer Research Group (GEICAM) Headquarters, Avenida De los Pirineos 7, 28703 San Sebastián de los Reyes, Madrid, Spain.
P RosadoMedical Oncology Unit, Hospital Puerta del Mar, Avenida Ana De Viya 21, 11009 Cádiz, Spain.
E DíazMedical Oncology Unit, Hospital Virgen del Rocío, Avenida Maneul Siurot S/N, 41013 Sevilla, Spain.
V GuillemMedical Oncology Unit, Instituto Valenciano de Oncología, C/Profesor Beltrán Baguena 19, 46009 Valencia, Spain.
E CarrascoSpanish Breast Cancer Research Group (GEICAM) Headquarters, Avenida De los Pirineos 7, 28703 San Sebastián de los Reyes, Madrid, Spain.
B Pérez-Gómez1] Cancer Epidemiology Unit, National Center for Epidemiology, Instituto de Salud Carlos III, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [2] Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Av/Monforte de Lemos, 5, 28029 Madrid, Spain.
J Vioque1] Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Carlos III Institute of Health, Av/Monforte de Lemos, 5, 28029 Madrid, Spain [2] Department of Public Health, Universidad Miguel Hernandez, Ctra. Alicante-Valencia, Km. 87, 03550 Sant Joan D'Alacant, Spain.
H BoeingDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.
M Martín1] Medical Oncology Unit, Hospital Clínico Universitario San Carlos, Calle Profesor Martín Lagos, S/N, 28040 Madrid, Spain [2] Health Research Institute Gregorio Marañón, Universidad Complutense, Calle Doctor Esquerdo 46, 28007 Madrid, Spain.
GEICAM researchers
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESBreast Cancer Research Foundation · USFundación Instituto Valenciano de Oncología · ESGerman Institute of Human Nutrition · DEHospital Universitario Puerta del Mar · ESHospital Universitario Virgen del Rocío · ESCentro Oncológico de Galicia · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínic de Barcelona · ESHospital General Universitario Gregorio Marañón · ESHospital Universitario Fundación Alcorcón · ESMarqués de Valdecilla University Hospital · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough there are solid findings regarding the detrimental effect of alcohol consumption, the existing evidence on the effect of other dietary factors on breast cancer (BC) risk is inconclusive. This study aimed to evaluate the association between dietary patterns and risk of BC in Spanish women, stratifying by menopausal status and tumour subtype, and to compare the results with those of Alternate Healthy Index (AHEI) and Alternate Mediterranean Diet Score (aMED).

methodsWe recruited 1017 incident BC cases and 1017 matched healthy controls of similar age (±5 years) without a history of BC. The association between 'a priori' and 'a posteriori' developed dietary patterns and BC in general and according to menopausal status and intrinsic tumour subtypes (ER+/PR+ and HER2-; HER2+; and ER-/PR- and HER2-) was evaluated using logistic and multinomial regression models.

resultsAdherence to the Western dietary pattern was related to higher risk of BC (OR for the top vs the bottom quartile 1.46 (95% CI 1.06-2.01)), especially in premenopausal women (OR=1.75; 95% CI 1.14-2.67). In contrast, the Mediterranean pattern was related to a lower risk (OR for the top quartile vs the bottom quartile 0.56 (95% CI 0.40-0.79)). Although the deleterious effect of the Western pattern was similarly observed in all tumour subtypes, the protective effect of our Mediterranean pattern was stronger for triple-negative tumours (OR=0.32; 95% CI 0.15-0.66 and Pheterogeneity=0.04). No association was found between adherence to the Prudent pattern and BC risk. The associations between 'a priori' indices and BC risk were less marked (OR for the top vs the bottom quartile of AHEI=0.69; 95% CI 0.51-0.94 and aMED=0.74; 95% CI 0.46-1.18)).

conclusionsOur results confirm the harmful effect of a Western diet on BC risk, and add new evidence on the benefits of a diet rich in fruits, vegetables, legumes, oily fish and vegetable oils for preventing all BC subtypes, and particularly triple-negative tumours.

Indexed as

Diet, MediterraneanCase-Control StudiesFemaleHumansIncidenceRiskSpainTriple Negative Breast Neoplasms

Identifiers

PMID25101568
PMCPMC4183855
OpenAlexW1986766753

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.