ArticleHeart rhythm2014
Electrogram morphology recurrence patterns during atrial fibrillation.
Article in Heart rhythm, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Catheter Ablation With Morphologic Repetitiveness Mapping for Persistent Atrial Fibrillation.JAMA network open · 2023Trial
- Mechanistic Insights From Trials of Atrial Fibrillation Ablation: Charting a Course for the Future.Circulation. Arrhythmia and electrophysiology · 2024Review
- Selecting repetitive focal and rotational activation patterns with the highest probability of being a source of atrial fibrillation.Journal of molecular and cellular cardiology plus · 2024Article
- Comparison of electrogram characteristics in persistent atrial fibrillation.Journal of cardiovascular electrophysiology · 2024Article
- Electrogram morphology recurrence guided catheter ablation for repeat ablation of persistent atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024Article
- Quantifying a spectrum of clinical response in atrial tachyarrhythmias using spatiotemporal synchronization of electrograms.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Electrogram Morphology Recurrence for Mapping Persistent Atrial Fibrillation: Initial vs Redo Catheter Ablation.JACC. Clinical electrophysiology · 2023Article
- Reply: Electrogram Morphology Recurrence and Cycle Length in AF Mapping: From Recurring Concepts to Clinical Practice?JACC. Basic to translational science · 2023Article
- Electrogram Morphology Recurrence: A Step Forward or Just a Recurrent Story?JACC. Basic to translational science · 2023Article
- Regions of Highly Recurrent Electrogram Morphology With Low Cycle Length Reflect Substrate for Atrial Fibrillation.JACC. Basic to translational science · 2023Article
- An Evaluation of Phase Analysis to Interpret Atrial Activation Patterns during Persistent Atrial Fibrillation for Targeted Ablation.Journal of clinical medicine · 2022Article
- Automatic Extraction of Recurrent Patterns of High Dominant Frequency Mapping During Human Persistent Atrial Fibrillation.Frontiers in physiology · 2021Article
- Article
- A novel framework for noninvasive analysis of short-term atrial activity dynamics during persistent atrial fibrillation.Medical & biological engineering & computing · 2020Article
- Focal impulse and rotor modulation of atrial rotors during atrial fibrillation leads to organization of left atrial activation as reflected by waveform morphology recurrence quantification analysis and organizational index.Journal of arrhythmia · 2020Article
- A Novel Tool for the Identification and Characterization of Repetitive Patterns in High-Density Contact Mapping of Atrial Fibrillation.Frontiers in physiology · 2020Article
- Region-specific parasympathetic nerve remodeling in the left atrium contributes to creation of a vulnerable substrate for atrial fibrillation.JCI insight · 2019Article
- Stationary Atrial Fibrillation Properties in the Goat Do Not Entail Stable or Recurrent Conduction Patterns.Frontiers in physiology · 2018Article
- The continuous challenge of AF ablation: From foci to rotational activity.Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology · 2017Review
- Mechanistic targets for the ablation of atrial fibrillation.Global cardiology science & practice · 2017Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundTraditional mapping of atrial fibrillation (AF) is limited by changing electrogram morphologies and variable cycle lengths.
objectiveWe tested the hypothesis that morphology recurrence plot analysis would identify sites of stable and repeatable electrogram morphology patterns.
methodsAF electrograms recorded from left atrial (LA) and right atrial (RA) sites in 19 patients (10 men; mean age 59 ± 10 years) before AF ablation were analyzed. Morphology recurrence plots for each electrogram recording were created by cross-correlation of each automatically detected activation with every other activation in the recording. A recurrence percentage, the percentage of the most common morphology, and the mean cycle length of activations with the most recurrent morphology were computed.
resultsThe morphology recurrence plots commonly showed checkerboard patterns of alternating high and low cross-correlation values, indicating periodic recurrences in morphologies. The mean recurrence percentage for all sites and all patients was 38 ± 25%. The highest recurrence percentage per patient averaged 83 ± 17%. The highest recurrence percentage was located in the RA in 5 patients and in the LA in 14 patients. Patients with sites of shortest mean cycle length of activations with the most recurrent morphology in the LA and RA had ablation failure rates of 25% and 100%, respectively (hazard ratio 4.95; P = .05).
conclusionA new technique to characterize electrogram morphology recurrence demonstrated that there is a distribution of sites with high and low repeatability of electrogram morphologies. Sites with rapid activation of highly repetitive morphology patterns may be critical to sustaining AF. Further testing of this approach to map and ablate AF sources is warranted.
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