Evidence map›Paper›PMID 25101302›Full record

ReviewBioMed research international2014

MicroRNAs: novel players in cancer diagnosis and therapies.

Aaron L Oom, Brock A Humphries, Chengfeng Yang

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
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  5. Review
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  8. Review
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  11. Knockdown ofCancer management and research · 2020
    Article
  12. Small non-coding RNA and colorectal cancer.Journal of cellular and molecular medicine · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aaron L OomDepartment of Physiology, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-3300-0333
Brock A HumphriesDepartment of Physiology, Michigan State University, East Lansing, MI 48824, USA ; Cellular and Molecular Biology Graduate Program, Michigan State University, East Lansing, MI 48824, USA.
Chengfeng YangDepartment of Physiology, Michigan State University, East Lansing, MI 48824, USA ; Cellular and Molecular Biology Graduate Program, Michigan State University, East Lansing, MI 48824, USA ; Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0002-2196-6854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.

Indexed as

Gene Expression Regulation, NeoplasticBiomarkers, TumorDrug Resistance, NeoplasmHumansMicroRNAsMolecular Targeted TherapyNeoplasmsBiomarkers, TumorMicroRNAs

Identifiers

PMID25101302
PMCPMC4101974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.