Evidence map›Paper›PMID 25101293›Full record

ReviewBioMed research international2014

Diagnosis, treatment, and outcome in patients with bleeding peptic ulcers and Helicobacter pylori infections.

Ting-Chun Huang, Chia-Long Lee

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. [Guidelines for Non-variceal Upper Gastrointestinal Bleeding].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020
    Guideline
  3. Traditional Chinese medicine in the treatment ofWorld journal of gastroenterology · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Prevalence ofInternational journal of general medicine · 2021
    Article
  8. Review
  9. Accuracy of theTherapeutic advances in gastroenterology · 2020
    Review
  10. Article
  11. Immunosuppressive agents are associated with peptic ulcer bleeding.Experimental and therapeutic medicine · 2017
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ting-Chun HuangDivision of Gastroenterology, Department of Internal Medicine, Cathay General Hospital, Taipei 10650, Taiwan ; School of Medicine, Fu-Jen Catholic University, New Taipei City 24205, Taiwan.ORCID 0000-0002-7866-1410
Chia-Long LeeDivision of Gastroenterology, Department of Internal Medicine, Cathay General Hospital, Taipei 10650, Taiwan ; Division of Gastroenterology, Department of Internal Medicine, Hsinchu Cathay General Hospital, No. 678, Section 2, Junghua Road, Hsinchu 30060, Taiwan ; School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-8556-024X
Cathay General Hospital · TWFu Jen Catholic University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper gastrointestinal (UGI) bleeding is the most frequently encountered complication of peptic ulcer disease. Helicobacter pylori (Hp) infection and nonsteroidal anti-inflammatory drug (NSAID) administration are two independent risk factors for UGI bleeding. Therefore, testing for and diagnosing Hp infection are essential for every patient with UGI hemorrhage. The presence of the infection is usually underestimated in cases of bleeding peptic ulcers. A rapid urease test (RUT), with or without histology, is usually the first test performed during endoscopy. If the initial diagnostic test is negative, a delayed (13)C-urea breath test (UBT) or serology should be performed. Once an infection is diagnosed, antibiotic treatment is advocated. Sufficient evidence supports the concept that Hp infection eradication can heal the ulcer and reduce the likelihood of rebleeding. With increased awareness of the effects of Hp infection, the etiologies of bleeding peptic ulcers have shifted to NSAID use, old age, and disease comorbidity.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalHelicobacter InfectionsHelicobacter pyloriHumansPeptic UlcerPeptic Ulcer HemorrhageRisk FactorsUreaseAnti-Inflammatory Agents, Non-SteroidalUrease

Identifiers

PMID25101293
PMCPMC4101224
OpenAlexW2167146530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.