Evidence map›Paper›PMID 25101216›Full record

ArticleBacteriophage2014

Inactivation of

Rachael M Tomb, Michelle Maclean, Paul R Herron, Paul A Hoskisson, Scott J MacGregor, John G Anderson

Abstract read
In one paragraph

Article in Bacteriophage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Light-based technologies for management of COVID-19 pandemic crisis.Journal of photochemistry and photobiology. B, Biology · 2020
    Review
  11. Spectrum of virucidal activity from ultraviolet to infrared radiation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2020
    Article
  12. Review
  13. Enhancement of Contact Lens Disinfection by Combining Disinfectant with Visible Light Irradiation.International journal of environmental research and public health · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Assessment of the potential for resistance to antimicrobial violet-blue light inAntimicrobial resistance and infection control · 2017
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rachael M TombThe Robertson Trust Laboratory for Electronic Sterilisation Technologies; University of Strathclyde; Glasgow, Scotland UK ; Strathclyde Institute of Pharmacy and Biomedical Sciences; University of Strathclyde; Glasgow, Scotland UK.
Michelle MacleanThe Robertson Trust Laboratory for Electronic Sterilisation Technologies; University of Strathclyde; Glasgow, Scotland UK.
Paul R HerronStrathclyde Institute of Pharmacy and Biomedical Sciences; University of Strathclyde; Glasgow, Scotland UK.
Paul A HoskissonStrathclyde Institute of Pharmacy and Biomedical Sciences; University of Strathclyde; Glasgow, Scotland UK.
Scott J MacGregorThe Robertson Trust Laboratory for Electronic Sterilisation Technologies; University of Strathclyde; Glasgow, Scotland UK.
John G AndersonThe Robertson Trust Laboratory for Electronic Sterilisation Technologies; University of Strathclyde; Glasgow, Scotland UK.
University of Strathclyde · GBThe Robertson Trust · GBGlasgow Life · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to narrowband violet-blue light around 405 nm wavelength can induce lethal oxidative damage to bacteria and fungi, however effects on viruses are unknown. As photosensitive porphyrin molecules are involved in the microbicidal inactivation mechanism, and since porphyrins are absent in viruses, then any damaging effects of 405 nm light on viruses might appear unlikely. This study used the bacteriophage ɸC31, as a surrogate for non-enveloped double-stranded DNA viruses, to establish whether 405 nm light can induce virucidal effects. Exposure of ɸC31 suspended in minimal media, nutrient-rich media, and porphyrin solution, demonstrated differing sensitivity of the phage. Significant reductions in phage titer occurred when exposed in nutrient-rich media, with ~3-, 5- and 7-log

Indexed as

405 nm lightbacteriophageinactivationphotosensitizersɸC31virus

Identifiers

PMID25101216
PMCPMC4116386
OpenAlexW1987901631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.