ArticleFrontiers in behavioral neuroscience2014
Hygienic grooming is induced by contact chemicals in Drosophila melanogaster.
Article in Frontiers in behavioral neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 78 citations in OpenAlex.
- Uracil-driven ROS signaling and larval TrpA1-B neuron activation are required for priming the adult Drosophila gustatory response to bacteria.PLoS biology · 2026Article
- Segmentally repeated ventral nerve cord circuits drive different leg rubbing behaviors iniScience · 2026Article
- Expanding the sensory horizon: chemosensory receptors beyond traditional olfactory and taste organs in insects.Science China. Life sciences · 2026Review
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- Genomic Signatures of Selection Across Climate Gradients and a Geographic Mosaic of Coevolution in an Ant Social Parasite-Host System.Molecular biology and evolution · 2025Article
- Capturing continuous, long timescale behavioral changes in Drosophila melanogaster postural data.PLoS computational biology · 2025Article
- Gustation in insects: taste qualities and types of evidence used to show taste function of specific body parts.Journal of insect science (Online) · 2023Article
- Host genetics and pathogen species modulate infection-induced changes in social aggregation behaviour.Biology letters · 2022Article
- Salmonella enterica changes Macrosteles quadrilineatus feeding behaviors resulting in altered S. enterica distribution on leaves and increased populations.Scientific reports · 2022Article
- Pre-copulatory reproductive behaviours are preserved inProceedings. Biological sciences · 2022Article
- Genetic Basis of Natural Variation in Spontaneous Grooming inG3 (Bethesda, Md.) · 2020Article
- Spatial Comparisons of Mechanosensory Information Govern the Grooming Sequence in Drosophila.Current biology : CB · 2020Article
- Recent advances in the genetic basis of taste detection in Drosophila.Cellular and molecular life sciences : CMLS · 2020Review
- Article
- Drosophila melanogaster grooming possesses syntax with distinct rules at different temporal scales.PLoS computational biology · 2019Article
- Chemosensory sensilla of the Drosophila wing express a candidate ionotropic pheromone receptor.PLoS biology · 2019Article
- Sexual Dimorphisms in Innate Immunity and Responses to Infection inFrontiers in immunology · 2019Review
- TRP Channels as Sensors of Bacterial Endotoxins.Toxins · 2018Review
- Article
- UsingFrontiers in cellular neuroscience · 2018Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In social insects, grooming is considered as a behavioral defense against pathogen and parasite infections since it contributes to remove microbes from their cuticle. However, stimuli which trigger this behavior are not well characterized yet. We examined if activating contact chemoreceptive sensilla could trigger grooming activities in Drosophila melanogaster. We monitored the grooming responses of decapitated flies to compounds known to activate the immune system, e.g., dead Escherichia coli (Ec) and lipopolysaccharides (LPS), and to tastants such as quinine, sucrose, and salt. LPS, quinine, and Ec were quite effective in triggering grooming movements when touching the distal border of the wings and the legs, while sucrose had no effect. Contact chemoreceptors are necessary and sufficient to elicit such responses, as grooming could not be elicited by LPS in poxn mutants deprived of external taste sensilla, and as grooming was elicited by light when a channel rhodopsin receptor was expressed in bitter-sensitive cells expressing Gr33a. Contact chemoreceptors distributed along the distal border of the wings respond to these tastants by an increased spiking activity, in response to quinine, Ec, LPS, sucrose, and KCl. These results demonstrate for the first time that bacterial compounds trigger grooming activities in D. melanogaster, and indicate that contact chemoreceptors located on the wings participate in the detection of such chemicals.
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