ArticlePsychophysiology2014
Taking the pulse of aging: mapping pulse pressure and elasticity in cerebral arteries with optical methods.
Article in Psychophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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Who cites it
47 citing papers in PubMed, 78 citations in OpenAlex.
- Ultrafast fMRI Detects Age-Related Changes in Harmonics of Cardiac Pulsations in the Brain at 7 T.Magnetic resonance in medicine · 2026Article
- Regional cerebral arterial elasticity is associated with cardiovascular health in cognitively healthy older adults.bioRxiv : the preprint server for biology · 2026Article
- Region-specific associations between cerebral arterial elasticity and grey matter volume: Evidence for lateral prefrontal vulnerability.bioRxiv : the preprint server for biology · 2025Article
- Ultrafast fMRI detects age-related changes in harmonics of cardiac pulsations in the brain at 7 T.bioRxiv : the preprint server for biology · 2025Article
- Effects of Aging, Estimated Fitness, and Cerebrovascular Status on White Matter Microstructural Health.Human brain mapping · 2025Article
- Age group classification based on optical measurement of brain pulsation using machine learning.Scientific reports · 2025Article
- Cerebral pulsatility might be a driver of neurofunctional reorganization in the aging brain: an MRI and NIRS study.Frontiers in aging neuroscience · 2025Article
- Neurovascular mechanisms of cognitive aging: Sex-related differences in the average progression of arteriosclerosis, white matter atrophy, and cognitive decline.Neurobiology of disease · 2024Article
- High caloric intake improves neuronal metabolism and functional hyperemia in a rat model of early AD pathology.Theranostics · 2024Article
- Enhancing diffuse correlation spectroscopy pulsatile cerebral blood flow signal with near-infrared spectroscopy photoplethysmography.Neurophotonics · 2023Article
- Cerebral blood flow predicts multiple demand network activity and fluid intelligence across the adult lifespan.Neurobiology of aging · 2023Article
- Biomolecular Markers of Brain Aging.Advances in experimental medicine and biology · 2023Article
- Psychedelics and fNIRS neuroimaging: exploring new opportunities.Neurophotonics · 2023Article
- Getting Fit to Counteract Cognitive Aging: Evidence and Future Directions.Physiology (Bethesda, Md.) · 2022Review
- Brain Metabolic Alterations in Alzheimer's Disease.International journal of molecular sciences · 2022Review
- Characterising activity and diet compositions for dementia prevention: protocol for the ACTIVate prospective longitudinal cohort study.BMJ open · 2022Article
- Long-term effects of multiple concussions on prefrontal cortex oxygenation during neurovascular coupling activation in retired male contact sport athletes.Current research in physiology · 2022Article
- A healthy mind in a healthy body: Effects of arteriosclerosis and other risk factors on cognitive aging and dementia.The psychology of learning and motivation · 2022Article
- Coronary artery disease and its impact on the pulsatile brain: A functional NIRS study.Human brain mapping · 2021Article
- Indexing cerebrovascular health using near-infrared spectroscopy.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Cerebrovascular support is crucial for healthy cognitive and brain aging. Arterial stiffening is a cause of reduced brain blood flow, a predictor of cognitive decline, and a risk factor for cerebrovascular accidents and Alzheimer's disease. Arterial health is influenced by lifestyle factors, such as cardiorespiratory fitness (CRF). We investigated new noninvasive optical measures of cerebrovascular health, which provide estimates of arterial pulse parameters (pulse pressure, transit time, and compliance/elasticity) within specific cerebral arteries and cortical regions, and low-resolution maps of large superficial cerebral arteries. We studied naturally occurring variability in these parameters in adults (aged 55-87), and found that these indices of cerebrovascular health are negatively correlated with age and positively with CRF and gray and white matter volumes. Further, regional pulse transit time predicts specific neuropsychological performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.