ArticleNature medicine2014
Lightening up a notch: Notch regulation of energy metabolism.
Article in Nature medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Genetic variation in NOTCH1 is associated with overweight and obesity in Brazilian elderly.Scientific reports · 2024Article
- SLC35D3 promotes white adipose tissue browning to ameliorate obesity by NOTCH signaling.Nature communications · 2023Article
- Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer.Nature communications · 2021Article
- Notch1 haploinsufficiency in mice accelerates adipogenesis.Scientific reports · 2021Article
- NOTCH Receptors and DLK Proteins Enhance Brown Adipogenesis in Mesenchymal C3H10T1/2 Cells.Cells · 2020Article
- Inhibiting the Notch signaling pathway suppresses Th17-associated airway hyperresponsiveness in obese asthmatic mice.Laboratory investigation; a journal of technical methods and pathology · 2019Article
- Complement and T Cell Metabolism: Food for Thought.Immunometabolism · 2019Article
- DLK proteins modulate NOTCH signaling to influence a brown or white 3T3-L1 adipocyte fate.Scientific reports · 2018Article
- Curcumin suppresses Notch‑1 signaling: Improvements in fatty liver and insulin resistance in rats.Molecular medicine reports · 2018Article
- Notch activation drives adipocyte dedifferentiation and tumorigenic transformation in mice.The Journal of experimental medicine · 2016Article
- Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules.Scientific reports · 2016Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Inhibiting Notch signaling induces adipose browning, improves systemic glucose tolerance and insulin sensitivity, and suppresses weight gain in mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.