ArticleThe American journal of clinical nutrition2014
Cross-sectional analysis of calcium intake for associations with vascular calcification and mortality in individuals with type 2 diabetes from the Diabetes Heart Study.
Article in The American journal of clinical nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- The effect of dietary micronutrient intake on abdominal aortic calcification: a study protocol for systematic review and meta-analysis.BMJ open · 2025Article
- Is it advisable for Asians to drink milk, especially those at risk of osteoporosis?Frontiers in nutrition · 2025Review
- Associations of Dietary Calcium and Phosphorus With Vascular and Valvular Calcification: The ARIC Study.JACC. Advances · 2024Article
- Article
- The Bone-Vasculature Axis: Calcium Supplementation and the Role of Vitamin K.Frontiers in cardiovascular medicine · 2019Review
- Association between Dietary Intake and Coronary Artery Calcification in Non-Dialysis Chronic Kidney Disease: The PROGREDIR Study.Nutrients · 2018Article
- The association of calcium supplementation and incident cardiovascular events in the Multi-ethnic Study of Atherosclerosis (MESA).Nutrition, metabolism, and cardiovascular diseases : NMCD · 2016Article
- Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes.Diabetes · 2016Review
- Calcium intake: good for the bones but bad for the heart? An analysis of clinical studies.Archives of endocrinology and metabolism · 2016Review
- Current understanding of coronary artery calcification.Journal of geriatric cardiology : JGC · 2015Review
- A review of the effect of diet on cardiovascular calcification.International journal of molecular sciences · 2015Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe use of calcium supplements to prevent declines in bone mineral density and fractures is widespread in the United States, and thus reports of elevated cardiovascular disease (CVD) risk in users of calcium supplements are a major public health concern. Any elevation in CVD risk with calcium supplement use would be of particular concern in individuals with type 2 diabetes (T2D) because of increased risks of CVD and fractures observed in this population.
objectiveIn this study, we examined associations between calcium intake from diet and supplements and measures of subclinical CVD (calcified plaque in the coronary artery, carotid artery, and abdominal aorta) and mortality in individuals affected by T2D.
designWe performed a cross-sectional analysis in individuals affected by T2D from the family-based Diabetes Heart Study (n = 720).
resultsWe observed no significant associations of calcium from diet or supplements with any of our measures of calcified plaque, and no greater mortality risk was observed with increased calcium intake. Instead, calcium supplement use was modestly associated with reduced all-cause mortality in women (HR: 0.62; 95% CI: 0.42, 0.92; P = 0.017).
conclusionOur results do not support a substantial association between calcium intake from diet or supplements and CVD risk in individuals with T2D.
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