Evidence map›Paper›PMID 25099524›Full record

ArticleInternational urology and nephrology2014

Association between non-alcoholic fatty liver disease and chronic kidney disease in population with prediabetes or diabetes.

Yongqiang Li, Shuangshuang Zhu, Bin Li, Xiaofei Shao, Xinyu Liu, Aiqun Liu, Bifang Wu, Ying Zhang, Honglei Wang, Xiaohong Wang and 6 more

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In one paragraph

Article in International urology and nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Yongqiang LiDepartment of Nephronology, Institute of Nephronology and Urology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, 510630, China, liyongqiang851@163.com.
Shuangshuang Zhu
Bin Li
Xiaofei Shao
Xinyu Liu
Aiqun Liu
Bifang Wu
Ying Zhang
Honglei Wang
Xiaohong Wang
Kangping Deng
Qin Liu
Min Huang
Hongmei Liu
Harry Holthöfer
Hequn Zou
Southern Medical University · CNThird Affiliated Hospital of Southern Medical University · CNDublin City University · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe relationship between chronic kidney disease (CKD) and non-alcoholic fatty liver disease (NAFLD) in population with diabetes remains controversial. Our current study aimed to explore the association between NAFLD and CKD in population with prediabetes or diabetes.

methodsA cross-sectional study was conducted in Zhuhai city from June to October 2012. A total of 190 out of 334 participants with prediabetes or diabetes were enrolled in this study. CKD was defined as estimated GFR <60 ml/min per 1.73 m(2) and/or albumin-to-creatinine ratio ≥ 30 mg/g. NAFLD was diagnosed on the basis of ultrasonographic and excluded fatty liver disease caused by other reasons such as drinking. The association between NAFLD and CKD was then analyzed using SPSS (version 19.0).

resultsSubjects with NAFLD were more likely with a higher urinary albumin-to-creatinine ratio (P < 0.001). CKD were common among patients with NAFLD than those without NAFLD (P < 0.05). NAFLD was significantly associated with CKD (P < 0.05) in the unadjusted analyses as well as after adjustment for potential confounders. The unadjusted odd ratio and adjusted odd ratio for CKD were 2.25 (95 % CI 1.07-4.77, P = 0.034) and 2.68 (95 % CI 1.12-6.01, P = 0.016). When further adjusted for hypertension, serum high-density lipoprotein and serum fasting glucose, the association of NAFLD with CKD was still significant (OR 2.78, 95 % CI 1.03-7.52, P = 0.044).

conclusionsOur current study suggests that ultrasound-diagnosed NAFLD is associated with CKD among population with prediabetes or diabetes.

Indexed as

Cross-Sectional StudiesDiabetes ComplicationsFemaleHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseasePrediabetic StateRenal Insufficiency, ChronicUltrasonography

Identifiers

PMID25099524
OpenAlexW2093336162

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.