Evidence map›Paper›PMID 25099513›Full record

ArticleJournal of neurology2014

Endolymphatic space size in patients with vestibular migraine and Ménière's disease.

Takafumi Nakada, Tadao Yoshida, Kenji Suga, Masahiro Kato, Hironao Otake, Ken Kato, Masaaki Teranishi, Michihiko Sone, Saiko Sugiura, Kayao Kuno and 5 more

Abstract read
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In one paragraph

Article in Journal of neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

  1. Pooled it
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  5. Imaging endolymphatic space of the inner ear in vestibular migraine.Journal of neurology, neurosurgery, and psychiatry · 2025
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  16. Recurrent vestibulopathy: are cVEMP, oVEMP and inner ear MRI useful to distinguish patients with Menière's disease and vestibular migraine?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Takafumi NakadaDepartment of Otorhinolaryngology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-ku, Nagoya, 466-8550, Japan, tnakada@med.nagoya-u.ac.jp.
Tadao Yoshida
Kenji Suga
Masahiro Kato
Hironao Otake
Ken Kato
Masaaki Teranishi
Michihiko Sone
Saiko Sugiura
Kayao Kuno
Ilmari Pyykkö
Shinji Naganawa
Hirohisa Watanabe
Gen Sobue
Tsutomu Nakashima
Nagoya University · JPKamiichi General Hospital · JPNational Center for Geriatrics and Gerontology · JPTampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ménière's disease (MD) is characterized by episodic vertigo, fluctuating hearing loss and tinnitus. Vestibular migraine (VM) is a relatively new disorder that is characterized by episodic vertigo or dizziness, coexisting migraine and absence of hearing loss. It is occasionally difficult to distinguish between VM and vestibular MD with headache. Because endolymphatic hydrops (EH) is a characteristic sign of MD, we attempted to evaluate endolymphatic space size in both diseases. Endolymphatic space size in the vestibule and the cochlea was evaluated in seven patients with VM and in seven age- and sex-matched patients with vestibular MD. For visualization of the endolymphatic space, 3T magnetic resonance imaging was taken 4 h after intravenous injection of gadolinium contrast agents using three-dimensional fluid-attenuated inversion recovery and HYbriD of reversed image of positive endolymph signal and native image of positive perilymph signal techniques. In the vestibule of VM patients, EH was not observed, with the exception of two patients with unilateral or bilateral EH. In contrast, in the vestibule of patients with vestibular MD, all patients had significant EH, bilaterally or unilaterally. These results indicate that endolymphatic space size is significantly different between patients with VM and vestibular MD.

Indexed as

AdultAgedEndolymphatic HydropsFemaleHumansMaleMeniere DiseaseMiddle AgedMigraine DisordersVestibule, LabyrinthYoung Adult

Identifiers

PMID25099513
OpenAlexW1985846530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.