Evidence map›Paper›PMID 25099096›Full record

ReviewContinuum (Minneapolis, Minn.)2014

Inflammatory optic neuropathies.

Fiona Costello

Registry-linked trialAbstract readCase ReportsReview
In one paragraph

Review in Continuum (Minneapolis, Minn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04942002 (Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis. Randomized Controlled Trial.), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04942002 phase2 / phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis. Randomized Controlled Trial.

TypeinterventionalSponsorAsociación para Evitar la Ceguera en MéxicoRan2021 to 2023Enrolled50ConditionsOptic Neuritis, Treatment, MethylprednisoloneArmsMethylprednisolone Acetate 40 MG/ML [Depo-Medrol], Placebo Comparator: Standard treatment + placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Eyeing the brain.Acta neuropathologica · 2016
    Article
  7. Neuroimaging in the Diagnostic Evaluation of Eye Pain.Current pain and headache reports · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Fiona Costello

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe aim of this review is to highlight the clinical presentation of a variety of inflammatory optic neuropathies through a case-based format. While emphasis will be placed on optic neuritis, which represents the most common acquired inflammatory optic nerve injury, the cardinal clinical features of other demyelinating forms of optic neuropathy and potential mimics for typical optic neuritis will be discussed. RECENT

findingsNovel developments in the diagnostic evaluation, clinical associations, and treatment options for several inflammatory optic neuropathies will be described. Key points will emphasize clinical pearls and potential pitfalls that may thwart early diagnosis of underlying demyelinating, infectious, and inflammatory diseases presenting with optic nerve involvement. SUMMARY: This review will aid the clinician in identifying potential red flags that should prompt consideration for causes of inflammatory optic nerve injury linked to neurologic and systemic disorders, and help guide safe and effective management for these conditions.

Indexed as

AdultFemaleHumansInflammationMagnetic Resonance ImagingMaleMiddle AgedNervous System DiseasesOptic Nerve Diseases

Identifiers

PMID25099096
PMCPMC10564073

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.