ArticleAddiction (Abingdon, England)2014
Genetic influences on alcohol-related hangover.
Article in Addiction (Abingdon, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- An event-level investigation of hangovers' relationship to age and drinking.Experimental and clinical psychopharmacology · 2015Pooled it
- Will I Have a Hangover Headache Tomorrow? A Prospective Cohort Study of the Predictors of Delayed Alcohol-Induced Headache.Life (Basel, Switzerland) · 2025Article
- The Relationship Between Alcohol Hangover Frequency and Hangover Severity.Journal of clinical medicine · 2025Article
- Hangover-Related Internet Searches Before and During the COVID-19 Pandemic in England: Observational Study.JMIR formative research · 2023Article
- The Role of Alcohol Metabolism in the Pathology of Alcohol Hangover.Journal of clinical medicine · 2020Review
- Effects of Rapid Recovery on Alcohol Hangover Severity: A Double-Blind, Placebo-Controlled, Randomized, Balanced Crossover Trial.Journal of clinical medicine · 2020Article
- Updating the Definition of the Alcohol Hangover.Journal of clinical medicine · 2020Article
- The Association between Alcohol Hangover Frequency and Severity: Evidence for Reverse Tolerance?Journal of clinical medicine · 2019Article
- The effects of alcohol hangover on future drinking behavior and the development of alcohol problems.Addictive behaviors · 2018Article
- Characterization of hangover following intravenous alcohol exposure in social drinkers: methodological and clinical implications.Addiction biology · 2018Article
- Hangover Symptoms, Heavy Episodic Drinking, and Depression in Young Adults: A Cross-Lagged Analysis.Journal of studies on alcohol and drugs · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
aimsTo quantify the relative contributions of genetic and environmental factors to alcohol hangover.
designBiometric models were used to partition the variance in hangover phenotypes.
settingA community-based sample of Australian twins.
participantsMembers of the Australian Twin Registry, Cohort II who reported consuming alcohol in the past year when surveyed in 2004-07 (n = 4496). MEASUREMENTS: Telephone interviews assessed participants' frequency of drinking to intoxication and frequency of hangover the day after drinking. Analyses examined three phenotypes: hangover frequency, hangover susceptibility (i.e. residual variance in hangover frequency after accounting for intoxication frequency) and hangover resistance (a dichotomous variable defined as having been intoxicated at least once in the past year with no reported hangovers).
findingsGenetic factors accounted for 45% [95% confidence interval (CI) = 37-53%] and 40% (95% CI = 33-48%) of the variation in hangover frequency in men and women, respectively. Most of the genetic variation in hangover frequency overlapped with genetic contributions to intoxication frequency. Genetic influences accounted for 24% (95% CI = 14-35%) and 16% (95% CI = 8-25%) of the residual hangover susceptibility variance in men and women, respectively. Forty-three per cent (95% CI = 22-63%) of the variation in hangover resistance was explained by genetic influences, with no evidence for significant sex differences. There was no evidence for shared environmental influences for any of the hangover phenotypes.
conclusionsIndividual differences in the propensity to experience a hangover and of being resistant to hangover at a given level of alcohol use are genetically influenced.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.