Evidence map›Paper›PMID 25098433›Full record

ArticleFrontiers of medicine2015

A case of primary neuroendocrine breast carcinoma that responded to neo-adjuvant chemotherapy.

Xiaolong Wei, Chunfa Chen, Didi Xi, Jinwen Bai, Wenhe Huang, Luoxiang Rong, Mingyao Wu, Guojun Zhang

Abstract readCase Reports
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In one paragraph

Article in Frontiers of medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Primary Neuroendocrine Carcinoma of Breast: Changing Paradigm.Indian journal of surgical oncology · 2025
    Article
  2. Review
  3. Neuroendocrine neoplasms of the breast: a review of literature.Virchows Archiv : an international journal of pathology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Neuroendocrine breast carcinoma: a rare but challenging entity.Medical oncology (Northwood, London, England) · 2020
    Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaolong WeiDepartment of Pathology, Cancer Hospital of Shantou University Medical College, Shantou, 515031, China.
Chunfa Chen
Didi Xi
Jinwen Bai
Wenhe Huang
Luoxiang Rong
Mingyao Wu
Guojun Zhang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary neuroendocrine breast carcinoma (NEBC) is a very rare type of breast cancer. Two characteristic biomarkers, namely, CgA and Syn, should be immunohistochemically detected to diagnose NEBC. In this study, a 43-year-old woman with a large mass of 8.3 cm × 2.9 cm in her right breast was reported. The patient was pathologically diagnosed with NEBC after specific markers, including CgA and Syn, as well as few differential markers, such as CK7, ER, PR, C-erbB-2, NSE, and E-cadherin, were immunohistochemically detected. The patient showed a remarkable response to four cycles of neo-adjuvant chemotherapy (partial response based on RECIST criteria) and sequentially underwent modified radical mastectomy. Moreover, the diagnosis and treatment of NEBC based on this case and available related literature were discussed.

Indexed as

Breast NeoplasmsCarcinoma, NeuroendocrineAdultBiomarkers, TumorChemotherapy, AdjuvantChromogranin AFemaleHumansImmunohistochemistryMammographyMastectomy, Modified RadicalSynaptophysinTreatment OutcomeBiomarkers, TumorChromogranin ASynaptophysin

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.