Evidence map›Paper›PMID 25097850›Full record

ArticleAsia Pacific allergy2014

Reference ranges for induced sputum eosinophil counts in Korean adult population.

Mi-Yeong Kim, Eun-Jung Jo, Seung-Eun Lee, Suh-Young Lee, Woo-Jung Song, Tae-Wan Kim, Gyu-Young Hur, Jae-Hyung Lee, Tae-Bum Kim, Heung-Woo Park and 4 more

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Article in Asia Pacific allergy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mi-Yeong KimDepartment of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Busan 614-735, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea.
Eun-Jung JoDepartment of Internal Medicine, Pusan National University College of Medicine, Busan 626-870, Korea.
Seung-Eun LeeDepartment of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan 626-700, Korea.
Suh-Young LeeInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Woo-Jung SongInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Tae-Wan KimInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Gyu-Young HurDepartment of Internal Medicine, Korea University College of Medicine, Seoul 136-705, Korea.
Jae-Hyung LeeDepartment of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul 139-711, Korea.
Tae-Bum KimDepartment of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea.
Heung-Woo ParkInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Yoon-Seok ChangInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam 463-707, Korea.
Hae-Sim ParkDepartment of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon 443-721, Korea.
Kyung-Up MinInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.
Sang-Heon ChoInstitute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 110-799, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInduced sputum analyses are widely utilized to evaluate airway inflammation in asthmatics. However, the values have not been examined in Korean adults.

objectiveThe purpose of this study is to determine reference ranges for induced sputum eosinophils and their influencing factors in Korean adults.

methodsA total of 208 healthy nonasthmatic adults were recruited. Sputum induction and processing followed the international standard protocols.

resultsAdequate sputum samples were successfully collected from 81 subjects (38.9%). The upper 90 percentile for sputum eosinophil was calculated as 3.5%. The median value of eosinophil count percentage was significantly higher in subjects with atopy than those without atopy (median, 1.6%; range, 0-11.0% vs. median, 0%; range 0-3.6%, p=0.030). However, no significant correlations were found with age, gender, body mass index, smoking status, blood eosinophil, or fractional exhaled nitric oxide levels.

conclusionCurrent study was the first attempt to determine the reference ranges of induced sputum eosinophils in Korean adults. The cutoff value for sputum eosinophilia was 3.5%, and was significantly associated with atopy.

Indexed as

EosinophilsHealthy volunteersReference valuesSputum

Identifiers

PMID25097850
PMCPMC4116041

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.