Evidence map›Paper›PMID 25097799›Full record

ArticleAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)

Developments in Ocular Genetics: 2013 Annual Review.

Inas F Aboobakar, R Rand Allingham

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Inas F AboobakarDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
R Rand AllinghamDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
Duke Medical Center · US

Funding

Gene Discovery in Primary Congenital GlaucomaR01EY023646 · NEI · DUKE UNIVERSITY · PI ALLINGHAM, ROBERT RAND, HAUSER, MICHAEL A · 2013 to 2015
$1.3M
NEI NIH HHS R01 EY023646
6 · The paper itself

Abstract

purposeTo highlight major advancements in ocular genetics from the year 2013.

designLiterature review.

methodsA literature search was conducted on PubMed to identify articles pertaining to genetic influences on human eye diseases. This review focuses on manuscripts published in print or online in the English language between January 1, 2013 and December 31, 2013. A total of 120 papers from 2013 were included in this review.

resultsSignificant progress has been made in our understanding of the genetic basis of a broad group of ocular disorders, including glaucoma, age-related macular degeneration, cataract, diabetic retinopathy, keratoconus, Fuchs' endothelial dystrophy, and refractive error.

conclusionsThe latest next-generation sequencing technologies have become extremely effective tools for identifying gene mutations associated with ocular disease. These technological advancements have also paved the way for utilization of genetic information in clinical practice, including disease diagnosis, prediction of treatment response and molecular interventions guided by gene-based knowledge.

Indexed as

age-related macular degenerationcataractdiabetic retinopathyepigeneticsFuchs’ endothelial corneal dystrophyGenome-wide association study (GWAS)glaucomakeratoconusmeta-analysisrefractive erroruveal melanomawhole-exome sequencing

Identifiers

PMID25097799
PMCPMC4119463
OpenAlexW2062798764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.