Evidence map›Paper›PMID 25097796›Full record

ReviewVeterinary medicine international2014

Mycoplasma agalactiae, an Etiological Agent of Contagious Agalactia in Small Ruminants: A Review.

Amit Kumar, Anu Rahal, Sandip Chakraborty, Amit Kumar Verma, Kuldeep Dhama

Open access · goldAbstract readReview
In one paragraph

Review in Veterinary medicine international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 50 citations in OpenAlex.

  1. Isolation and molecular characterization of Mycoplasma ovipneumoniae associated with respiratory infection in sheep and goats in South India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  2. Article
  3. Vaccines · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Detecting Mollicutes by PCR in goats in southwestern Bahia, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  13. A novel chimeric recombinant protein PDHB-P80 ofMolecular biology research communications · 2020
    Article
  14. SynMyco transposon: engineering transposon vectors for efficient transformation of minimal genomes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019
    Article
  15. Contagious Agalactia In Sheep And Goats: Current Perspectives.Veterinary medicine (Auckland, N.Z.) · 2019
    Review
  16. A review of mycoplasma diagnostics in cattle.Journal of veterinary internal medicine · 2018
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Amit KumarDepartment of Veterinary Microbiology, Uttar Pradesh Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidhyalaya Evum Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.
Anu RahalDivision of Pharmacology and Toxicology, Indian Veterinary Research Institute, Izatnagar 243122, India.
Sandip ChakrabortyAnimal Resources Development Department, Pt. Nehru Complex, Agartala 799006, India.ORCID 0000-0002-0175-5320
Amit Kumar VermaDepartment of Veterinary Epidemiology and Preventive Medicine, Uttar Pradesh Pandit Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidhyalaya Evum Go-Anusandhan Sansthan (DUVASU), Mathura 281001, India.
Kuldeep DhamaDivision of Pathology, Indian Veterinary Research Institute, Izatnagar 243122, India.ORCID 0000-0001-7469-4752
Indian Veterinary Research Institute · INUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mycoplasma agalactiae is one of the causal agents of classical contagious agalactia (CA), a serious, economically important but neglected enzootic disease of small ruminants. It occurs in many parts of the world and most notably in the Mediterranean Basin. Following the infection common complications are septicaemia, mastitis, arthritis, pleurisy, pneumonia, and keratoconjunctivitis. Primary or tentative diagnosis of the organism is based upon clinical signs. Various serological tests, namely, growth precipitation, immunofluorescence, complement fixation test, haemagglutination inhibition, agglutination, immunodiffusion, enzyme immunoassays, immunoelectrophoresis, blotting techniques, and others, are available. Molecular tools seem to be much more sensitive, specific, and faster and help to differentiate various strains. The real-time PCR, multiplex PCR, quantitative PCR, PCR-RFLP, MLST, and gene probes, complementary to segments of chromosomal DNA or 16S ribosomal RNA (rRNA), have strengthened the diagnosis of M. agalactiae. Both live attenuated and adjuvant (alum precipitated or saponified) inactivated vaccines are available with greater use of inactivated ones due to lack of side effects. The present review discusses the etiology, epidemiology, pathogenesis, and clinical signs of contagious agalactia in small ruminants along with trends and advances in its diagnosis, treatment, vaccination, prevention, and control strategies that will help in countering this disease.

Identifiers

PMID25097796
PMCPMC4109668
OpenAlexW2166902159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.