ReviewInterface focus2014
Bacteria and game theory: the rise and fall of cooperation in spatially heterogeneous environments.
Review in Interface focus, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Navigating complexity: key considerations for studying fungal-bacterial interactions.mSystems · 2026Article
- Sociobiology meets oncology: unraveling altruistic cooperation in cancer cells and its implications.Experimental & molecular medicine · 2025Review
- Chondroitin Sulfate and Proteinoids in Neuron Models.ACS applied bio materials · 2025Article
- Review
- The role of recognition error in the stability of green-beard genes.Evolution letters · 2023Article
- Cancer's second genome: Microbial cancer diagnostics and redefining clonal evolution as a multispecies process: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution: Humans and their tumors are not aseptic, and the multispecies nature of cancer modulates clinical care and clonal evolution.BioEssays : news and reviews in molecular, cellular and developmental biology · 2022Review
- Game theory applications in host-microbe interactions toward disease manifestation:Iranian journal of basic medical sciences · 2021Article
- The unexplored bacterial lifestyle on leaf surface.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Review
- Structured environments fundamentally alter dynamics and stability of ecological communities.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Do Organic Substrates Drive Microbial Community Interactions in Arctic Snow?Frontiers in microbiology · 2019Article
- On-Chip Isoniazid Exposure ofMicromachines · 2018Article
- Conditional privatization of a public siderophore enables Pseudomonas aeruginosa to resist cheater invasion.Nature communications · 2018Article
- Application of Microfluidics in Experimental Ecology: The Importance of Being Spatial.Frontiers in microbiology · 2018Review
- Spatial organization of a model 15-member human gut microbiota established in gnotobiotic mice.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Synthetic Ecology of Microbes: Mathematical Models and Applications.Journal of molecular biology · 2016Review
- Cheating is evolutionarily assimilated with cooperation in the continuous snowdrift game.Bio Systems · 2015Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the predictions of game theory is that cooperative behaviours are vulnerable to exploitation by selfish individuals, but this result seemingly contradicts the survival of cooperation observed in nature. In this review, we will introduce game theoretical concepts that lead to this conclusion and show how the spatial competition dynamics between microorganisms can be used to model the survival and maintenance of cooperation. In particular, we focus on how Escherichia coli bacteria with a growth advantage in stationary phase (GASP) phenotype maintain a proliferative phenotype when faced with overcrowding to gain a fitness advantage over wild-type populations. We review recent experimental approaches studying the growth dynamics of competing GASP and wild-type strains of E. coli inside interconnected microfabricated habitats and use a game theoretical approach to analyse the observed inter-species interactions. We describe how the use of evolutionary game theory and the ideal free distribution accurately models the spatial distribution of cooperative and selfish individuals in spatially heterogeneous environments. Using bacteria as a model system of cooperative and selfish behaviours may lead to a better understanding of the competition dynamics of other organisms-including tumour-host interactions during cancer development and metastasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.