ArticleDental research journal2014
Serum lipid profile in patients with oral cancer and oral precancerous conditions.
Article in Dental research journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07005115 (Analysis of Serum Lipid Profile in Patients With Lip Squamous Cell Carcinoma), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analysis of Serum Lipid Profile in Patients With Lip Squamous Cell Carcinoma
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Serum lipid alterations in oral squamous cell carcinoma and oral potentially malignant disorders: A systematic review and meta-analysis.Scientific reports · 2026Pooled it
- The effects of prednisolone treatment on serological responses and lipid profiles in Ethiopian leprosy patients with Erythema Nodosum Leprosum reactions.PLoS neglected tropical diseases · 2018Trial
- Lipid homeostasis dysregulation in oral cancer drives metabolic reprogramming and offers novel diagnostic and therapeutic opportunities.Discover oncology · 2025Review
- Association of Oral Health Determinants With Oral Squamous Cell Carcinoma in Never-Smoking Adults.Head & neck · 2025Article
- Dietary factors and oral cancer risk: a comprehensive Mendelian randomization analysis in a European population.Discover oncology · 2025Article
- Microenvironment in Oral Potentially Malignant Disorders: Multi-Dimensional Characteristics and Mechanisms of Carcinogenesis.International journal of molecular sciences · 2022Review
- Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.PLoS genetics · 2021Article
- Optical diagnosis of oral cavity lesions by label-free Raman spectroscopy.Biomedical optics express · 2021Article
- Alterations of Serum Lipid Profile Patterns in Oral Lichen Planus Patients: A Case-Control Study.Contemporary clinical dentistry · 2018Article
- Synthetic high-density lipoprotein-like nanoparticles for cancer therapy.Expert review of anticancer therapy · 2015Review
- Serum biochemical profiling in tobacco-exposed individuals: Evaluating metabolic alterations and gamma-glutamyl transferase as an early marker of oxidative stress.Journal of oral and maxillofacial pathology : JOMFPArticle
- Lipid profile in oral potentially malignant disorders and oral squamous cell carcinoma - A prognostic view.Journal of oral and maxillofacial pathology : JOMFPArticle
- New diagnostic markers in basal cell carcinoma.Journal of oral and maxillofacial pathology : JOMFPArticle
- Diagnostic significance of serum and salivary lipid levels in oral precancer and oral cancer.National journal of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study was undertaken to estimate and compare the levels of plasma total cholesterol (TC), low density lipoprotein (LDL), high density lipoprotein (HDL), very low density lipoprotein (VLDL) and triglycerides in patients with oral precancerous lesions/conditions, oral cancer and normal subjects. MATERIALS AND
methodsThe study comprised of 60 patients with oral precancerous lesions/conditions, 60 patients with oral cancer and a control group of 60 healthy individuals. The diagnosis of oral precancerous lesions/conditions and oral cancer was confirmed histopathologically. Under aseptic condition 5 ml venous blood of overnight fasting patient was withdrawn from each individual. Serum was separated by centrifugation and plasma levels of TC, LDL, HDL, VLDL and triglycerides were estimated. Descriptive statistical analysis has been carried out in the present study. Analysis of variance has been used to find the significance of study parameters between three or more groups of patients, Post-hoc test as Tukey has been used to find the pair wise significance. Significance is assessed at 5% level of significance.
resultsStatistically significant decrease in levels of plasma TC, LDL, HDL, VLDL and triglycerides was observed in the precancerous and cancerous groups as compared to the control group. On comparison between precancerous and cancerous groups, significant decrease was observed in cancerous group.
conclusionThe change in lipid levels may have an early diagnostic or prognostic role in the oral premalignant lesions/conditions and oral cancer. The presence of decreased plasma lipid profile should increase the suspicion of these lesions to be investigated further.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.