ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2014
Insulin and leptin levels in overweight and normal-weight Iranian adolescents: The CASPIAN-III study.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Combined resistance and aerobic exercise training reduces insulin resistance and central adiposity in adolescent girls who are obese: randomized clinical trial.European journal of applied physiology · 2018Trial
- Effects of dietary copper intake on blood lipids in women of childbearing age and the potential role of gut microbiota.Frontiers in nutrition · 2024Article
- Brief Report: Plasma Leptin and Mealtime Feeding Behaviors Among Children with Autism Spectrum Disorder: A Pilot Study.Journal of autism and developmental disorders · 2023Article
- Peripubertal Alterations of Leptin Levels in Patients with Autism Spectrum Disorder and Elevated or Normal Body Weight.International journal of molecular sciences · 2023Article
- miR-10a-3p modulates adiposity and suppresses adipose inflammation through TGF-β1/Smad3 signaling pathway.Frontiers in immunology · 2023Article
- Adipokines as Immune Cell Modulators in Multiple Sclerosis.International journal of molecular sciences · 2021Review
- Obesity is associated with copper elevation in serum and tissues.Metallomics : integrated biometal science · 2019Article
- Associations of serum leptin, ghrelin and peptide YY levels with physical activity and cardiorespiratory fitness in adolescent boys with different BMI values.Biology of sport · 2017Article
- An overview on the successes, challenges and future perspective of a national school-based surveillance program: the CASPIAN study.Journal of diabetes and metabolic disorders · 2014Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn this study, we aim to compare insulin and leptin levels in adolescents with or without excess weight and in those with or without abdominal obesity. MATERIALS AND
methodsThis case-control study was conducted among 486 samples. We randomly selected 243 overweight and an equal number of normal-weight adolescents from among participants of the third survey of a national surveillance program entitled Childhood and Adolescence Surveillance and PreventIon of Adult Non-communicable diseases study. Serum insulin and leptin were compared between two groups and their correlation was determined with other variables.
resultsThe mean age and body mass index (BMI) of participants were 14.10 ± 2.82 years and 22.12 ± 6.49 kg/m(2), respectively. Leptin and insulin levels were higher in overweight than in normal-weight adolescents (P < 0.05). Leptin level was higher in children with abdominal obesity than in their other counterparts (P < 0.001). Leptin level was correlated with age, fasting blood glucose, BMI, and insulin level.
conclusionInsulin and leptin levels were higher among overweight and obese children, which may reflect insulin and leptin-resistance. Given the complications of excess weight from early life, prevention and controlling childhood obesity should be considered as a health priority.
Indexed as
Identifiers
25097618PMC4116567W2097398523What OpenQuestion holds
Registered trials
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