Evidence map›Paper›PMID 25097473›Full record

ReviewPostepy dermatologii i alergologii2014

Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis.

Bogusław Nedoszytko, Małgorzata Sokołowska-Wojdyło, Katarzyna Ruckemann-Dziurdzińska, Jadwiga Roszkiewicz, Roman J Nowicki

Open access · goldAbstract readReview
In one paragraph

Review in Postepy dermatologii i alergologii, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 141 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 2 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 2 syntheses or guidelines pooled it, 280 citations in OpenAlex.

  1. Interventions for postburn pruritus.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Contribution of Immune Responses toJournal of inflammation research · 2026
    Article
  8. Article
  9. Article
  10. International journal of molecular sciences · 2025
    Article
  11. Therapeutic Effects ofInternational journal of molecular sciences · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. International journal of molecular sciences · 2024
    Article
  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Bogusław NedoszytkoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman J. Nowicki MD, PhD.
Małgorzata Sokołowska-WojdyłoDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman J. Nowicki MD, PhD.
Katarzyna Ruckemann-DziurdzińskaDepartment of Pathology and Experimental Rheumatology, Medical University of Gdansk, Poland. Head of Department: Prof. Ewa Bryl MD, PhD.
Jadwiga RoszkiewiczDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman J. Nowicki MD, PhD.
Roman J NowickiDepartment of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman J. Nowicki MD, PhD.
Gdańsk Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines are signaling peptides which regulate cell trafficking and provide control of the tissue-specific cell homing. In the skin, chemokines are secreted both by the resident cells such as keratinocytes, melanocytes, fibroblasts, dendritic cells and mast cells, as well as by infiltrated cells - lymphocytes, eosinophils, and monocytes. Chemokines, together with cytokines, participate in induction and maintenance of inflammation in the skin and regulate the composition of the cellular infiltrates. Inflammation within the skin is a feature shared by atopic dermatitis and psoriasis, two of the most common dermatoses. Accumulation of activated mast cells in the affected skin is seen both in atopic dermatitis and in psoriasis. This paper presents a concise overview of the current knowledge on the role chemokines have in pathogenesis of atopic dermatitis, psoriasis, and mastocytosis, a disease caused directly by the accumulation and activation of mast cells in the skin.

Indexed as

atopic dermatitischemokinecytokinesmastocytosispsoriasis

Identifiers

PMID25097473
PMCPMC4112246
OpenAlexW2120115895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.