ReviewCurrent hypertension reports2014
Renal generation of angiotensin II and the pathogenesis of hypertension.
Review in Current hypertension reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Upregulation of angiotensin-(1-7) formation in human podocytes - enzyme activity assay upon fluid flow shear stress.PloS one · 2026Article
- Bioactive Constituents and Antihypertensive Mechanisms of Zhengan Xifeng Decoction: Insights from Plasma UPLC-MS, Network Pharmacology and Molecular Dynamics Simulations.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Beyond LDL-C: discordant small dense LDL cholesterol stratifies hypertension risk in a Chinese longitudinal cohort.Lipids in health and disease · 2025Article
- Article
- Targeting GPR39 in structure-based drug discovery reduces Ang II-induced hypertension.Communications biology · 2024Article
- Serum uric acid is independently associated with hypertension in patients with polymyositis and dermatomyositis.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Angiotensin II and dengue.Archives of virology · 2023Review
- Biomarkers involved in the pathogenesis of cerebral small-vessel disease.Frontiers in neurology · 2022Review
- Molecular Mechanisms Involved in Intrarenal Renin-Angiotensin and Alternative Pathways in Diabetic Nephropathy - A Review.The review of diabetic studies : RDS · 2021Review
- Mechanisms of Metabolic Acidosis-Induced Kidney Injury in Chronic Kidney Disease.Journal of the American Society of Nephrology : JASN · 2020Article
- Molecular Mechanisms of Kidney Injury and Repair in Arterial Hypertension.International journal of molecular sciences · 2019Review
- Long-term low salt diet increases blood pressure by activation of the renin-angiotensin and sympathetic nervous systems.Clinical and experimental hypertension (New York, N.Y. : 1993) · 2019Article
- Unraveling the Physiology of (Pro)Renin Receptor in the Distal Nephron.Hypertension (Dallas, Tex. : 1979) · 2017Review
- Gastrointestinal-Renal Axis: Role in the Regulation of Blood Pressure.Journal of the American Heart Association · 2017Review
- Antihypertensive Effects of Roselle-Olive Combination in L-NAME-Induced Hypertensive Rats.Oxidative medicine and cellular longevity · 2017Article
- Long-term antihypertensive effects of far-infrared ray irradiated from wooden board in spontaneously hypertensive rats.BMC complementary and alternative medicine · 2016Article
- Article
- Maintaining Balance Under Pressure: Integrated Regulation of Renal Transporters During Hypertension.Hypertension (Dallas, Tex. : 1979) · 2015Review
- G protein-coupled receptor kinase 4: role in hypertension.Hypertension (Dallas, Tex. : 1979) · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
The existence of a complete and functional renin-angiotensin system along the nephron is widely recognized. However, its precise role in blood pressure control and, by extension, hypertension is still uncertain. While most investigators agree that overexpressing RAS components along the nephron results in hypertension, two important issues remain: whether the local RAS works as a separate entity or represents an extension of the systemic RAS and whether locally generated angiotensin II has specific renal effects on blood pressure that are distinct from systemic angiotensin II. This review addresses these issues while emphasizing the unique role of local angiotensin II in the response of the kidney to hypertensive stimuli and the induction of hypertension.
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Registered trials
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