ArticleParasites & vectors2014
Protein profile of lambs experimentally infected with Haemonchus contortus and supplemented with selenium and copper.
Article in Parasites & vectors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 16 citations in OpenAlex.
- Effects of Medicinal Plants and Organic Selenium against Ovine Haemonchosis.Animals : an open access journal from MDPI · 2021Article
- Influence of metabolizable protein and minerals supplementation on detrimental effects of endoparasitic nematodes infection in small ruminants.Tropical animal health and production · 2020Review
- Effect of experimental nematode infection on serum mineral concentrations in growing lambs.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2019Article
- Microbial community and ovine host response varies with early and late stages of Haemonchus contortus infection.Veterinary research communications · 2017Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGastrointestinal nematodes cause significant economic losses in the sheep industry, with frequent reports of anthelmintic resistance. Therefore, alternative methods to control these parasites are necessary. Thus, the aim of the present study was to assess the effect of treatment with selenium and copper on the protein profile of sheep that were experimentally infected with Haemonchus contortus.
methodsTwenty-eight lambs were experimentally infected with H. contortus and divided into four experimental groups as follow: G1--untreated animals; G2--treated with sodium selenite; G3--treated with copper; G4--treated with sodium selenite and copper. The serum protein, body weight and egg count per gram of feces (EPG) were assessed at the baseline and after 20, 40, 60 and 80 days. The parasite burden was assessed 80 days after the beginning of the experiment.
resultsHigher levels of total protein and gamma globulin were observed in the lambs treated with sodium selenite and copper on D80. Copper acted as a growth promoter. The copper-supplemented groups exhibited higher daily and total weight gain. The association of selenium and copper altered the protein profile of sheep. Copper and selenium supplementation reduced EPG and worm burden at the end of the experiment. To the best of our knowledge, this is the first study to demonstrate the positive effect of the combined parenteral supplementation of Se and Cu on H. contortus infection.
conclusionsThis injectable supplementation could be used as an auxiliary method to control H. contortus in sheep.
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