ArticlemBio2014
Do rumen Bacteroidetes utilize an alternative mechanism for cellulose degradation?
Article in mBio, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 144 citations in OpenAlex.
- Effect of Dietary Nitrogen-to-Sulfur Ratio on Rumen Microbiota, Metabolites, and Ruminal Antioxidant Status in Tibetan Sheep.Antioxidants (Basel, Switzerland) · 2026Article
- Alginate foraging is conserved in geographically and taxonomically distinct ruminant microbiomes.Nature communications · 2026Article
- A system for transferring large genetic loci inApplied and environmental microbiology · 2026Article
- Effects of Glycerol Fatty Acid Esters on Growth Performance, Methane Emissions, and Rumen Microbial Flora of Dabieshan Beef Cattle.Veterinary sciences · 2026Article
- A prototype bioreactor for the water retting of hemp bast fiber: dynamics of the liquor bacterial consortium across sequential retting cycles.Frontiers in plant science · 2026Article
- Effects of increasing levels of rubber seed cake on growth performance, nutrient digestion metabolism, serum biochemical parameters, and rumen microbiota of Hu sheep.BMC veterinary research · 2025Article
- Dietary resveratrol modulates rumen microbiota and metabolic function in Tibetan sheep: an integrated 16S rRNA sequencing and metabolomics analysis.Frontiers in microbiology · 2025Article
- Taxonomic and functional shifts in the rumen microbiome of buffalo calves under long-term strategic supplementation of phyto-feed additives.Frontiers in veterinary science · 2025Article
- Microbial consortia driving (ligno)cellulose transformation in agricultural woodchip bioreactors.Applied and environmental microbiology · 2024Article
- The contribution of seasonal variations and Zostera marina presence to the bacterial community assembly of seagrass bed sediments.BMC microbiology · 2024Article
- Profiling the dynamic adaptations of CAZyme-Producing microorganisms in the gastrointestinal tract of South African goats.Heliyon · 2024Article
- The Ruminal Microbiome Alterations Associated with Diet-Induced Milk Fat Depression and Milk Fat Globule Size Reduction in Dairy Goats.Animals : an open access journal from MDPI · 2024Article
- Effects of the alpine meadow in different phenological periods on rumen fermentation and gastrointestinal tract bacteria community in grazing yak on the Qinghai-Tibetan Plateau.BMC microbiology · 2024Article
- Dietary 5-hydroxytryptophan improves sheep growth performance by enhancing ruminal functions, antioxidant capacity, and tryptophan metabolism:Frontiers in immunology · 2024Article
- Effects ofFrontiers in microbiology · 2024Article
- Response of rumen fermentation and microbiota to dietary supplementation of sodium selenite and bio-nanostructured selenium in lactating Barki sheep.BMC veterinary research · 2023Article
- Effects of partially replacing dietary corn with sugars in a dual-flow continuous culture system on the ruminal microbiome.Translational animal science · 2023Article
- Prevotella: A Key Player in Ruminal Metabolism.Microorganisms · 2022Review
- Increasing buffering capacity enhances rumen fermentation characteristics and alters rumen microbiota composition of high-concentrate fed Hanwoo steers.Scientific reports · 2022Article
- Dietary Supplementation of Fruit fromAnimals : an open access journal from MDPI · 2022Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uncultured and therefore uncharacterized Bacteroidetes lineages are ubiquitous in many natural ecosystems which specialize in lignocellulose degradation. However, their metabolic contribution remains mysterious, as well-studied cultured Bacteroidetes have been shown to degrade only soluble polysaccharides within the human distal gut and herbivore rumen. We have interrogated a reconstructed genome from an uncultured Bacteroidetes phylotype that dominates a switchgrass-associated community within the cow rumen. Importantly, this characterization effort has revealed the first preliminary evidence for polysaccharide utilization locus (PUL)-catalyzed conversion of cellulose. Based on these findings, we propose a further expansion of the PUL paradigm and the saccharolytic capacity of rumen Bacteroidetes species to include cellulose, the most abundant terrestrial polysaccharide on Earth. Moreover, the perspective of a cellulolytic PUL lays the foundation for PULs to be considered an alternative mechanism for cellulose degradation, next to cellulosomes and free-enzyme systems.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.