Evidence map›Paper›PMID 25096831›Full record

ArticleScientific reports2014

A programmable closed-loop recording and stimulating wireless system for behaving small laboratory animals.

Gian Nicola Angotzi, Fabio Boi, Stefano Zordan, Andrea Bonfanti, Alessandro Vato

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Multi-disease Deep Brain Stimulation.IEEE access : practical innovations, open solutions · 2020
    Article
  6. A Miniature Dual-Biomarker-Based Sensing and Conditioning Device for Closed-Loop DBS.IEEE journal of translational engineering in health and medicine · 2019
    Article
  7. A Programmable Multi-biomarker Neural Sensor for Closed-loop DBS.IEEE access : practical innovations, open solutions · 2018
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Evolution of Neuroprosthetic Interfaces.Critical reviews in biomedical engineering · 2016
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gian Nicola Angotzi1] Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy [2] Department of Robotics, Brain and Cognitive Sciences, Istituto Italiano di Tecnologia, Genova, Italy.
Fabio Boi1] Center for Neuroscience and Cognitive Systems @UniTn, Istituto Italiano di Tecnologia, Rovereto, Italy [2] Department of Robotics, Brain and Cognitive Sciences, Istituto Italiano di Tecnologia, Genova, Italy.
Stefano ZordanDepartment of Robotics, Brain and Cognitive Sciences, Istituto Italiano di Tecnologia, Genova, Italy.
Andrea BonfantiDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Italy.
Alessandro Vato1] Center for Neuroscience and Cognitive Systems @UniTn, Istituto Italiano di Tecnologia, Rovereto, Italy [2] Department of Robotics, Brain and Cognitive Sciences, Istituto Italiano di Tecnologia, Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A portable 16-channels microcontroller-based wireless system for a bi-directional interaction with the central nervous system is presented in this work. The device is designed to be used with freely behaving small laboratory animals and allows recording of spontaneous and evoked neural activity wirelessly transmitted and stored on a personal computer. Biphasic current stimuli with programmable duration, frequency and amplitude may be triggered in real-time on the basis of the recorded neural activity as well as by the animal behavior within a specifically designed experimental setup. An intuitive graphical user interface was developed to configure and to monitor the whole system. The system was successfully tested through bench tests and in vivo measurements on behaving rats chronically implanted with multi-channels microwire arrays.

Indexed as

Brain-Computer InterfacesAction PotentialsAnimalsBehavior, AnimalElectric StimulationElectrodes, ImplantedEquipment DesignMaleRatsRats, Long-EvansRemote Sensing TechnologySignal Processing, Computer-AssistedSomatosensory CortexStereotaxic TechniquesWireless Technology

Identifiers

PMID25096831
PMCPMC4123143

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.