Evidence map›Paper›PMID 25096802›Full record

ArticleUrolithiasis2015

Micro-CT imaging of Randall's plaques.

James C Williams, James E Lingeman, Fredric L Coe, Elaine M Worcester, Andrew P Evan

Open access · greenAbstract read
In one paragraph

Article in Urolithiasis, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

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  17. Usefulness of measuring renal papillae in Hounsfield units in stone - forming patients.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

James C WilliamsDepartment of Anatomy and Cell Biology, Indiana University School of Medicine, 635 Barnhill Drive MS 5055Y, Indianapolis, IN, 46202-5120, USA, jwillia3@iupui.edu.
James E Lingeman
Fredric L Coe
Elaine M Worcester
Andrew P Evan
Indiana University – Purdue University Indianapolis · USUniversity of Chicago · USMethodist Hospital · US

Funding

STONE FORMATION IN GENETIC HYPERCALCIURIAP01DK056788 · NIDDK · UNIVERSITY OF CHICAGO · PI WILLIAMS, JAMES C · 2000 to 2021
$22.5M
The Structural Basis of Kidney Stone FragilityR01DK059933 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WILLIAMS, JAMES C · 2004 to 2011
$2.4M
NIDDK NIH HHS P01 DK056788NIDDK NIH HHS P01 DK5678NIDDK NIH HHS R01 DK059933
6 · The paper itself

Abstract

Micro-computed tomographic imaging (micro-CT) provides unprecedented information on stone structure and mineral composition. High-resolution micro-CT even allows visualization of the lumens of tubule and/or vessels within Randall's plaque, on stones or in papillary biopsies, thus giving a non-destructive way to study these sites of stone adhesion. This paper also shows an example of a stone growing on a different anchoring mechanism: a mineral plug within the lumen of a Bellini duct (BD plug). Micro-CT shows striking structural differences between stones that have grown on Randall's plaque and those that have grown on BD plugs. Thus, Randall's plaque can be distinguished by micro-CT, and this non-destructive method shows great promise in helping to elucidate the different mechanisms by which small stones are retained in the kidney during the development of nephrolithiasis.

Indexed as

X-Ray MicrotomographyCalcinosisHumansKidney CalculiKidney DiseasesKidney Medulla

Identifiers

PMID25096802
PMCPMC4285664
OpenAlexW2023204199

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.