ReviewMolecular biology reports2014
Structure, function, and epigenetic regulation of BNIP3: a pathophysiological relevance.
Review in Molecular biology reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 44 citations in OpenAlex.
- Mitocytosis, mitophagy, and apoptosis coordinately drive mitochondrial clearance to regulate myogenic differentiation.Journal of advanced research · 2026Article
- HIF-1 contributes to autophagy activation via BNIP3 to facilitate renal fibrosis in hypoxia in vitro and UUO in vivo.American journal of physiology. Cell physiology · 2024Article
- Pyrimethamine upregulates BNIP3 to interfere SNARE-mediated autophagosome-lysosomal fusion in hepatocellular carcinoma.Journal of pharmaceutical analysis · 2024Article
- Ionizing radiation triggers mitophagy to enhance DNA damage in cancer cells.Cell death discovery · 2023Article
- Emerging role of mitophagy in heart failure: from molecular mechanism to targeted therapy.Cell cycle (Georgetown, Tex.) · 2023Review
- Tax1 banding protein 1 exacerbates heart failure in mice by activating ITCH-P73-BNIP3-mediated cardiomyocyte apoptosis.Acta pharmacologica Sinica · 2022Article
- Advances in the mechanism and treatment of mitochondrial quality control involved in myocardial infarction.Journal of cellular and molecular medicine · 2021Review
- EBV-LMP1 promotes radioresistance by inducing protective autophagy through BNIP3 in nasopharyngeal carcinoma.Cell death & disease · 2021Article
- BNIP3 in Lung Cancer: To Kill or Rescue?Cancers · 2020Review
- Acheron/Larp6 Is a Survival Protein That Protects Skeletal Muscle From Programmed Cell Death During Development.Frontiers in cell and developmental biology · 2020Article
- Article
- Ten years of research on the role of BVES/ POPDC1 in human disease: a review.OncoTargets and therapy · 2019Review
- HIF-1α/Beclin1-Mediated Autophagy Is Involved in Neuroprotection Induced by Hypoxic Preconditioning.Journal of molecular neuroscience : MN · 2018Article
- DNA methylation of the promoter region of bnip3 and bnip3l genes induced by metabolic programming.BMC genomics · 2018Article
- A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3.Cell death & disease · 2018Article
- Methylation of BNIP3 in pancreatic cancer inhibits the induction of mitochondrial-mediated tumor cell apoptosis.Oncotarget · 2017Article
- CURRENT CONCEPTS ON THE GENETIC FACTORS IN ROTATOR CUFF PATHOLOGY AND FUTURE IMPLICATIONS FOR SPORTS PHYSICAL THERAPISTS.International journal of sports physical therapy · 2017Article
- Autophagy Induction Results in Enhanced Anoikis Resistance in Models of Peritoneal Disease.Molecular cancer research : MCR · 2017Article
- BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy.The Journal of biological chemistry · 2016Article
- Targeting BNIP3 in inflammation-mediated heart failure: a novel concept in heart failure therapy.Heart failure reviews · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BCL-2 [B-cell leukemia/lymphoma 2]/adenovirus E1B 19KD interacting protein 3 (BNIP3) is an atypical BH3 domain only containing member of Bcl2 family of proteins. BNIP3 is known to be involved in various cellular processes depending on the cell type and conditions and also shown to play a role in various disease conditions including myocardial ischemia, autophagy and apoptosis. Though its role in autophagy and its pro-death activity have been reported in various studies, recent findings have shown its contradictory role in the regulation of these cellular processes. The various studies have shown its epigenetic regulation in disease development and progression and also found to be cytoprotective. In this review, we have focused on the structural and functional aspects of BNIP3 in relation to recent advances of its role in autophagy and apoptosis. Also its role of epigenetic regulation of several genes involved in various diseases was also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.