ArticleDevelopmental cognitive neuroscience2015
The development of object recognition memory in rhesus macaques with neonatal lesions of the perirhinal cortex.
Article in Developmental cognitive neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Reevaluating the role of the hippocampus in memory: A meta-analysis of neurotoxic lesion studies in nonhuman primates.Hippocampus · 2023Pooled it
- Role of the Primate Perirhinal Cortex in Memory and Emotional Regulation: Ontogeny and Early Insults.Medical research archives · 2026Article
- Review
- Effects of temporal lobe seizures on visual recognition memory in a non-human primate model.Epilepsy & behavior : E&B · 2025Article
- Altered adult brain morphology in a mouse model of late-onset fetal growth restriction.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Review
- Activation for newly learned words in left medial-temporal lobe during toddlers' sleep is associated with memory for words.Current biology : CB · 2021Article
- Astrogliosis in juvenile non-human primates 2 years after infant anaesthesia exposure.British journal of anaesthesia · 2021Article
- Donecopride, a Swiss army knife with potential against Alzheimer's disease.British journal of pharmacology · 2020Article
- Impaired Cognitive Flexibility After Neonatal Perirhinal Lesions in Rhesus Macaques.Frontiers in systems neuroscience · 2019Article
- Intact perceptual ability, but impaired familiarity judgment, after neonatal perirhinal lesions in rhesus macaques.Developmental cognitive neuroscience · 2017Article
- Neonatal perirhinal cortex lesions impair monkeys' ability to modulate their emotional responses.Behavioral neuroscience · 2017Article
- Visual recognition memory is impaired in rhesus monkeys repeatedly exposed to sevoflurane in infancy.British journal of anaesthesia · 2017Article
- Development of relational memory processes in monkeys.Developmental cognitive neuroscience · 2016Article
- The extended trajectory of hippocampal development: Implications for early memory development and disorder.Developmental cognitive neuroscience · 2016Review
- Object and spatial memory after neonatal perirhinal lesions in monkeys.Behavioural brain research · 2016Article
- The development of hippocampal-dependent memory functions: Theoretical comments on Jabès and Nelson review (2015).International journal of behavioral development · 2015Article
- Neonatal Perirhinal Lesions in Rhesus Macaques Alter Performance on Working Memory Tasks with High Proactive Interference.Frontiers in systems neuroscience · 2015Article
- Long-term effects of neonatal hippocampal lesions on novelty preference in monkeys.Hippocampus · 2013Article
- Developmental trajectory of object recognition memory in infant rhesus macaques with and without neonatal hippocampal lesions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
To investigate the role of the perirhinal cortex on the development of recognition measured by the visual paired-comparison (VPC) task, infant monkeys with neonatal perirhinal lesions and sham-operated controls were tested at 1.5, 6, 18, and 48 months of age on the VPC task with color stimuli and intermixed delays of 10 s, 30 s, 60 s, and 120 s. Monkeys with neonatal perirhinal lesions showed an increase in novelty preference between 1.5 and 6 months of age similar to controls, although at these two ages, performance remained significantly poorer than that of control animals. With age, performance in animals with neonatal perirhinal lesions deteriorated as compared to that of controls. In contrast to the lack of novelty preference in monkeys with perirhinal lesions acquired in adulthood, novelty preference in the neonatally operated animals remained above chance at all delays and all ages. The data suggest that, although incidental recognition memory processes can be supported by the perirhinal cortex in early infancy, other temporal cortical areas may support these processes in the absence of a functional perirhinal cortex early in development. The neural substrates mediating incidental recognition memory processes appear to be more widespread in early infancy than in adulthood.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.